Fully Positive

If two random variables are nncorrelated, then both their covariance Cab and their correlation coefficient rab are equal to zero. If two random variables are fully correlated, then the absolute value of their covariance is C,J = cacb, and the absolute value of their correlation coefficient is unity rab = 1. A key point to note for our EPR linewidth theory to be developed is that two fully correlated variables can be fully positively correlated rab = 1, or fully negatively correlated rab = -1. Of course, if two random variables are correlated to some extent, then 0 < Cab < oacb, and 0 < IrJ < 1. 

If the distributions in D and E would be fully positively correlated, then no broadening of the EPR spectrum whatsoever would ensue, because their ratio (i.e., the rhombicity q = E/D) would remain constant, and so the effective -values would not be distributed. On the other hand, a maximal broadening effect would occur in case of full negative correlation oD = -aE. This definition reduces the description of /7-strain to the fitting of a single parameter. 

As noted earlier, the halogen-carbon bond in an alkyl halide is polarized due to the electronegativity difference between the atoms. This polarization can lead to the formation of a partial or fully positive charge on the carbon atom. 

There are no a-amino fluorides because of the reactivity of this functional combination, and for the same reason, there are few /1-amino fluorides. However, when attached to the less basic nitrogen of a benzimidazole or benzotriazole, the CH2F or CHFR groups are much more stable (Scheme 3.35). Note that when attached to a partially positive nitrogen, as in an imidazolium compound, or a fully positive ammonium nitrogen, the respective fluorines become progressively more shielded. a-Fluoroazides can be prepared but are also not very stable. 

HI at pi (5.97) the carboxyl group is fully negatively charged (deprotonated) and the amino group is fully positively charged (protonated). 

A 42-year-old woman with insuhn-dependent diabetes and chronic renal insufficiency developed pancreatitis 5 days after taking enalapril 2.5 mg and recovered after drug withdrawal. The pancreatitis relapsed one week after her general practitioner had prescribed losartan 50 mg/day, with full recovery after withdrawal. A rechallenge test with losartan was fully positive. 

The three common types of mold designs are open flash, fully positive, and semipositive. 

The semipositive mold (Figure 2.2c and d) combines certain features of the open flash and fully positive molds and makes allowance for excess powder and flash [4]. It is also possible to get both horizontal and vertical flash. Semipositive molds are more expensive to manufacture and maintain than the other types, but they are much better from an applications point of view. Satisfactory operation of semipositive molds is obtained by having clearance (0.025/25 mm of diameter) between the plunger (top force) and the cavity. Moreover, the mold is given a 2-3° taper on each side. This allows the flash to flow on and the entrapped gases to escape along with it, thereby producing a clean, blemish-free mold component. 

Fully Positive. Also called a direct positive mold (Fig. 10.5), this is solely used for large deep draw parts where maximum density must be obtained. These molds are limited to single eavity produe-tion requiring the weighing of eaeh material charge to assure the depth (or the height) and the density of the finished part. 

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