Fucose, occurrence

Vanhooren, P.T. and Vandamme, E.J. (1999) L-Fucose occurrence, physiological role, chemical, enzymatic and microbial synthesis. J. Chem. Technol. Biotechnol., 74, 479-497. 

Vieira, R. P. and Mourao, P. A. (1988). Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumber. J. Biol. Chem. 263,18176-18183. 

Deoxyketoses are of rare natural occurrence. The antibiotic hygromycin177 has been shown to contain 6-deoxy-D-arabmo-hexos-a-ulose residues, since reduction of the free sugar gave 6-deoxy-D-altrose and L-fucose. Yungsten and coworkers171 reported the isolation of a 6-deoxy-L-x2/io-hexulose (an-gustose) from the antibiotic Angustmycin A, for which structure (37) was proposed. 

Keratan sulfate consists of the disaccharide, iV-acetyl-lactosamine, linked /3-(1 3) to the D-galactopyranose residue of the next iV-acetyl-lactosamine unit. Keratan sulfate is the most heterogeneous of the glycosaminoglycans, with variable sulfate content linked to C-4 or C-6 of the D-galactop)Tanose residue in lactosamine, and small amounts of L-fucose (6-deoxy-L-galactose), D-mannose, and iV-acetyl-neuraminic acid residues [93] (also see Sects. 10.2 and O 14 on the occurrence of iV-acetyl-D-neuraminic acid and L-fucose in other systems). Keratan sulfate is found in the cornea, on the surfaces of erythrocytes, in cartilage, and in bone. 

I. B. H. Wilson, R. Zeleny, D. Kolarich, E. Staudacher, C. J. M. Stroop, J. P. Kamerling, and F. Altmann, Analysis of Asn-linked glycans from vegetable foodstuffs widespread occurrence of Lewis a, core al,3-linked fucose and xylose substitutions, Glycobiology, 11 (2001) 261-274. 

Glycosidic acid Oligosaccharide linked to jalapinolic add (Jal) glu = P-D-glucose rha = a-L-ihamnose fuc = P-D-fucose qui = P-D-quinovose Occurrence as component of resin glycosides (species) (discovery in bold)... 

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