Fritsche

B. V. Vora, P. R. Pujado, M. A. Allawala, and T. R. Fritsch, "Production of Biodegradable Detergent Intermediates," Second World Surfactants Congress, Paris, Fiance, May 24—27, 1988. 

J. Sambrook, E. F. Fritsch, and T. Maniatis, Molecular Cloning, 2nd ed.. Cold Spring Harbor Press, Cold Spring Harbor, N.Y., 1989. 

Poly (vinyl pyrrol idones) polymerization, 1, 271 Polyviologens synthesis, 1, 286 Pomeranz-Fritsch synthesis isoqutnolines, 2, 428 6, 218 Pongapin synthesis, 4, 710 Poranthericine, 4, 494 ( )-Porantherine synthesis, 2, 377 Porphin, 4, 386 structure, 4, 378 Porphin, mcso-aryltri-p-tolyl-synthesis, 4, 230 Porphin, mcso-tetraalkyl-synthesis, 4, 230 Porphin, mcso-tetraaryl-synthesis, 4, 230 Porphin, mcso-tetraferrocenyl-synthesis, 4, 230 Porphin, meso-tetraphenyl-synthesis, 7, 767 Porphobilinogen biosynthesis, 1, 100... 

Field scanning (light) Gilas, Goiilter, Insitec, Fritsch, Horiba, Leeds Northnip (Microtrac), Malvern, Nitto, Seishin, Shimadzu, Sympatec 0.04—.3500 im <1 g (wet) >20 g (on-line)... 

FRITSCH BUTTENBERG - WIECHELL Acetylene Synthesis Alpha elimination from haloethylenes leading via carbene rearrangement to acetylenes... 

POMERANZ - FRITSCH SCHLITTER MULLER I soquinoDna Synthesis... 

Without the dilution, (Z)-l,4-diphenyl-l-buten-3-yne is detected, apparently formed from the cross-coupling with phenyl acetylide, derived from lithiation of g-bromostyrene, followed by E2cB elimination or Fritsch-Butlenberg-Wiechell type rearrangement. 

Diem, H., Fritsch, R., Lehnert, H., Matthias, G., Schatz, H. and Wittmann, O., German patent DE 3125874. Process for the preparation of cocondensates which form weatherproof adhesive bonds. Assigned to BASF AG, 1981. 

Sambrook, J., Fritsch, E. R, and Maniati.s, T, 1989. Molecular Cloning, 2nd ed. Long Island Cold Spring Harbor Laboratory Press. (This cloning manual i.s familiarly referred to as Maniati.s. )... 

The Pomeranz-Fritsch reaction involves the preparation of isoquinolines 4 via the acid-mediated cyclisation of the appropriate aminoacetal intermediate 3. The best yields are usually obtained when the benzaldehyde portion 1 has electron-donating substituents in the 3- or 3,4- positions relative to the aldehyde. 

Of the well-known methods to prepare isoquinolines, including the Pictet-Spengler and Bischler-Napieralski cyclisation, the Pomeranz-Fritsch reaction is the only direct generally accepted method for the construction of the fully unsaturated isoquinoline ring system. 

Toward the end of the 19 century both Pomeranz and Fritsch independently reported the preparation of isoquinolines by the reaction of aminoacetaldehyde dimethyl acetal 2 (R = Me) with aromatic aldehydes 1 followed by cyclisation in acidic media. " Unfortunately yields were often poor and not always reproducible. This has prompted the search for various improvements and modifications on the original theme, including the use of reagents other than strong mineral acid which tends to destroy the intermediate imine. ... 

The Bobbitt modification is the most widely used variation of the Pomeranz-Fritsch reaction. This modification involves cyclisation of benzylaminoacetal 10, usually prepared from the classical Pomeranz-Fritsch imine 9, to yield 4-hydroxy derivatives 11. The success of this method can be attributed to avoiding treatment and thus (partial) destruction of imine 10 under strongly acidic conditions. 

The Jackson modification involves cyclisation of iV-tosylated amine 12 and provides a complementary method to the classical Pomeranz-Fritsch reaction for entry into the fully unsaturated ring system 13. Amine 12 can be prepared from either the Pomeranz-Fritsch-Bobbitt imine 10 or reaction of benzylhalide 14 and the corresponding sodium anion 15. ... 

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