Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Fluorometholone

Chemical Name 9-fluoro-11(3,17-dihydroxy-6o -methylpregna-1,4-diene-3,20-dione Common Name — [Pg.674]

Trade Name Manufacturer Country Year Introduced [Pg.675]

1 -Dehydro-6a-methyl-9a-fluorohydrocortisone Methanesulfonyl chloride Sodium iodide Sodium thiosulfate [Pg.675]

Fractions 11 through 24 inclusive were combined, evaporated and twice recrystallized from acetone to give pure 6a-methyl-9a-fluoro-11(3,17a-dihydroxy-1,4-pregnadiene-3,20-dione of melting point 292° to 303°C. [Pg.676]

Patent 2,852,511 September 16, 1958 assigned to Olin Mathieson Chemical Corporation [Pg.676]

The oxygen atom at 21 is similarly an expendable group. Reaction of 241 (obtained from 185 by the usual procedure for introduction of the 9a-fluoro group) with methanesulfonyl chloride affords the 21 mesylate (242a). Replacement of the leaving group at 21 with iodine by means of potassium iodide in acetone followed by reduction of the halogen with zinc in acetic acid leads to fluorometholone (243). ... [Pg.203]

Penicillin G hydrabamine Dehydroabietyl ethylene diamine Penicillin V hydrabamine 1 -Dehydro-6tt-methyl-9a-fluorohydro-cortisone Fluorometholone 6-Dehydro-17-methyltestosterone Calusterone... [Pg.1626]

Suspension. If the drug is not sufficiently soluble, it can be formulated as a suspension. A suspension may also be desired to improve stability, bioavailability, or efficacy. The major topical ophthalmic suspensions are the steroid anti-inflammatory agents prednisolone acetate, dexamethasone, fluorometholone, and rimex-olone. Water-soluble salts of prednisolone phosphate and dexamethasone phosphate are available however, they have a lower steroid potency and are poorly absorbed. [Pg.456]

Flucinolone Acetonide Fludrocortisone Acetate Fludroxycortide Flumethasone Fluocortolone Fluorometholone 9a-Fluoroprednisolone Acetate... [Pg.457]

Figure SAO), fluorometholone, which is 6a-Me-substituted, and fluprednidene, substituted in C-16 with an exo-methylene (Figure 8.43). [Pg.311]

See other pages where Fluorometholone is mentioned: [Pg.433]    [Pg.438]    [Pg.268]    [Pg.674]    [Pg.675]    [Pg.1687]    [Pg.1687]    [Pg.1689]    [Pg.1695]    [Pg.1696]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1701]    [Pg.1714]    [Pg.1725]    [Pg.1735]    [Pg.1750]    [Pg.1753]    [Pg.623]    [Pg.896]    [Pg.897]    [Pg.2386]    [Pg.2386]    [Pg.2387]    [Pg.2389]    [Pg.2406]    [Pg.424]    [Pg.452]    [Pg.481]    [Pg.1586]    [Pg.2096]    [Pg.2096]    [Pg.597]    [Pg.597]    [Pg.311]    [Pg.344]   
See also in sourсe #XX -- [ Pg.203 ]



SEARCH



Corticosteroids fluorometholone

Fluorometholone formulations

Fluorometholone/sulfacetamide

© 2024 chempedia.info