Fluorescent chemosensor, supramolecular

CONTENTS Preface. George W. Gokel. Cryptophanes Receptors for Tetrahedral Molecules, Andre Collett, Jean-Pierre Dutasta and Benedict Lozach. Inclusion Polymerization in Steroidal Canal Complexes, Kiichi Takemoto, Mikiji Miyata. Functionalized Tetraazamacrocycles Ligands with Many Aspects, Thomas A. Kaden. Calixarenes as the Third Supramolecular Host, Seiji Shinkai, Kyushu University, Japan. Fluorescent Chemosensors for Metal and Non-Metal Ions in Aqueous Solutions Based on the Chief Paradigm, Anthony W. Czamik. Index. 

A rational approach to developing a fluorescent chemosensor for potassium (K ) is presented. In this approach, J-M. Lehn s [222] cryptand, which selectively binds K, is covalently attached to coumarin at positions 6 and 7. In this hybrid system, coumarin plays the role of a transducer translating the free energy of supramolecular interaction between the cryptand and into measurable enhancement of its fluorescence. By Immobilizing this system on an optical fiber, the continuous monitoring of in patients undergoing open-heart surgery can be achieved. 

The great impact in metal-ion coordination chemistry caused by the discovery of the macrocyclic polyethers31 has led to new designs of chemosensors for the alkali cations. Application of a supramolecular receptor to fluorescence sensing was first... 

There has been considerable interest in the development of new methods of chemical sensing to recognize molecules or ions as important application of supramolecular chemistry [1-3]. Our group has prepared many kinds of chro-mophore-modified cyclodextrins (CD) as chemosensors for detecting molecules [4-8]. Colorless neutral molecules can be detected as changes in the intensities of the fluorescence, absorption, or circular dichroism using chemosensors based on chromophore-modified CD. 

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