Host supramolecular

The main supramolecular self-assembled species involved in analytical chemistry are micelles (direct and reversed), microemulsions (oil/water and water/oil), liposomes, and vesicles, Langmuir-Blodgett films composed of diphilic surfactant molecules or ions. They can form in aqueous, nonaqueous liquid media and on the surface. The other species involved in supramolecular analytical chemistry are molecules-receptors such as calixarenes, cyclodextrins, cyclophanes, cyclopeptides, crown ethers etc. Furthermore, new supramolecular host-guest systems arise due to analytical reaction or process. 

A by-product of the solvophobic collapse of the mPE backbone is the formation of a hydrophobic cavity. Similar cavities have been explored for use as hosts in molecular recognition however, these cavities are typically quite rigid and synthetically difficult to access [4, 6]. The formation of a hydrophobic cavity through supramolecular folding of the mPE backbone offers a modular platform for the study of small molecule binding with supramolecular hosts. 

CONTENTS Preface. George W. Gokel. Cryptophanes Receptors for Tetrahedral Molecules, Andre Collett, Jean-Pierre Dutasta and Benedict Lozach. Inclusion Polymerization in Steroidal Canal Complexes, Kiichi Takemoto, Mikiji Miyata. Functionalized Tetraazamacrocycles Ligands with Many Aspects, Thomas A. Kaden. Calixarenes as the Third Supramolecular Host, Seiji Shinkai, Kyushu University, Japan. Fluorescent Chemosensors for Metal and Non-Metal Ions in Aqueous Solutions Based on the Chief Paradigm, Anthony W. Czamik. Index. 

Upon binding the rates of rearrangement are accelerated for all substrates studied. The measured activation parameters of the reactions reveal that the supramolecular host can reduce both the entropic and the enthalpic barriers for the rearrangement. The capsule acts as a true catalyst, since release and hydrolysis facilitates turnover. 

Pluth, M.D. and Raymond, K.N. (2007) Reversible guest exchange mechanisms in supramolecular host-guest assemblies. Chem. Soc. Rev, 36 (2), 161-171. 

Brumaghim, J.L., Michels, M., Pagliero, D. and Raymond, K.N. (2004) Encapsulation and stabilization of reactive aromatic diazonium ions and the tropylium ion within a supramolecular host. Eur. J. Org. Chem., 5115-5118. 

Leung, D.H., Bergman, R.G. and Raymond, K.N. (2006) Scope and mechanism of the C—H bond activation reactivity within a supramolecular host by an iridium guest A stepwise ion pair guest dissociation mechanism. J. Am. Chem. Soc., 128 (30), 9781-9797. 

Pluth, M.D., Bergman, R.G. and Raymond, KN. (2007) Acid catalysis in basic solution A supramolecular host promotes orthoformate hydrolysis. Science, 316, 85-88. 

Fig. 6.37 Dendritic phthalocyanine 10 and supramolecular host-guest system 11 a,b (according to Kimura et al.)...

Figure 1.9 Supramolecular host-guest complexation stabilised by positive cooperativity between binding sites Ag+ binding by 1.12, a host for citrate anion (1.13) and a drug-receptor complex formed by vancomycin (1.14).

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