First Approaches and Adverse Analytical Findings

First official anti-doping rules as established by international federations became effective in 1966 (Federation Internationale de Football Association, FIFA) and 1967 (Union Cycliste Internationale, UCI Union Internationale de Pentathlon Modeme et Biathlon, UIPMB). Nevertheless, pilot studies with regard to human sports drug testing started as early as 1955, and systematic controls at great sporting events were initiated at the FIFA World Cup in 1966. At that time, the 

In order to enhance chromatographic properties of many target analytes with relevance to sports drug testing, numerous derivatives were prepared in the following years for instance from stimulants and steroids. The advantages of derivatization were manifold 

Occasion World Cnp (UK) General General Olympic Games (Grenoble / Mexico City) 

Although invented as early as 1953, ° the quadrupole mass spectrometer was not installed in doping control laboratories as detector in GC-MS systems until the late 1970s/early 1980s.Providing fast 

---