Ferrocene major applications

Major Applications of Ferrocene Diphosphine-Based Catalysts 1847... 

It is beyond the scope of this book to describe further the organic chemistry of ferrocene. There is much research interest at present in this field. The stability of the ferrocenyl group and the diversity of its reactions permit the preparation of a vast range of derivatives, although no major applications for them have yet been found. 

Summary of the Major Catalytic Applications of Ferrocene-Based Catalysts.300... 

SUMMARY OF THE MAJOR CATALYTIC APPLICATIONS OF FERROCENE-BASED CATALYSTS... 

Antonio Arques Adame was born in Badajoz in 1952. He studied chemistry at the University of Murcia (Spain), from where he also obtained his Ph.D. in 1980. He joined the group of Prof. P. Molina at the University of Murcia and from 1984 he held a position as an assistant professor at the University of Murcia. The major focus of his research interest relates to heterocyclic chemistry using iminophosphorane methodology. His current research interest is focused on the development of hetero-difunctional ferrocene-coordination ligands and their application to organic synthesis. 

Asymmetric synthesis has emerged as a major preparative method, widely used in organic chemistry and in the total synthesis of natural products, and which is also of interest for industrial chemistry. The importance of enantiomerically pure compounds is connected with the applications in pharmaceutical industries, since very often the biological activity is strongly linked to the absolute configuration. In this article the historical developments of asymmetric synthesis will be briefly presented, as well as the main methods to prepare enantiomerically enriched compounds. Then recent asymmetric synthesis of two classes of compounds will be discussed i) Sulfoxides, chiral at sulfur ii) Ferrocenes with planar chirality. The last part of the article will be devoted to asymmetric catalysis with transition-metal complexes. The cases of asymmetric oxidation of sulfides to sulfoxides and nonlinear effects in asymmetric catalysis will be mainly considered. 

Chiral phosphorus-containing dendrimers which have ferrocene molecules at the periphery have been the subject of work by Majoral and co-workers. These materials will have obvious applications in catalysis. Layer-by-layer dendrimers, which are built up containing chiral ferrocenylphosphine molecules, have also been prepared, and their chiroptical and electrochemical properties have been investigated. A recent article covers the basic chemistry of ferrocene-containing liquid-crystalline polymers which stems from the extensive work of Deschenaux, who essentially pioneered the area. A ferrocene end-capped dendrimer has also been used in carbon monoxide sensing. The actual dendrimer, shown as 19, has 48 ferrocene molecules on the periphery. 

Ferrocene, di-(ii -cyclopentadienyl)iron(II), a key representative of the class of organometallic compounds known as metallocenes, has found numerous divergent applications in science and technology. The compound owes this multivaried behavior pattern largely to its unusual electronic structure and resultant oxidation-reduction properties. Attracted by the challenges offered in the realm of the biosciences, a major stream of investigative activities, as shown in Section II of... 

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