FeCl3 hexahydrate

A very simple yet elegant method for efficient epoxidation of aromatic and aliphatic alkenes was presented by Beller and coworkers [63, 64], FeCl3 hexahydrate in combination with 2,6-pyridinedicarboxylic add and various organic amines gave a highly reactive and selective catalyst system. An asymmetric variant (for epoxidations of trans-stilbene and related aromatic alkenes) was published recently [65] using N-monosulfonylated diamines as chiral ligands (Scheme 3.7). 

Chemical Designations - Synonyms Ferric Chloride (anhydrous). Ferric Chloride (hexahydrate). Iron (in) chloride. Iron perchloride. Iron trichloride Chemical Formula FeClj or FeCl3 6H20. Observable Characteristics - Physical State (as shipped) Solid Color Anhydrous greenish black, Hidrate brown Odor None. 

Cu(II) or Fe(III) salts are applied as catalysts. In Scheme 8.30, the reaction of nitrile 41i with benzylamine gives an almost quantitative yield if FeCl3-7H20 is applied as the catalyst, which is, however, in contrast to the hexahydrate, not commercially available [98], Water is normally considered as an environmentally benign solvent. The authors curiously needed CFI2CI2 and other organic solvents for workup and purification of the product 67 (Scheme 8.30). 

Urushibara Fe,128 To a well-mixed zinc dust (25 g) and water (8 g) placed in a 50-ml beaker is added 9.68 g (2 g of Fe) of ferric chloride hexahydrate (FeCl3 6H2O). The mixture is then well stirred with a glass rod. Soon a vigorous exothermic reaction starts, but subsides within about 10 s. To complete the reaction, the mixture is stirred until the color of the ferric ion disappears. The reaction mixture is washed with 400... 

Iron(III) thiocyanate (0-05m). Dissolve 1-35 g iron(III) chloride hexahydrate, FeCl3.6H20, and 2 g potassium thiocyanate, KSCN, in water and dilute the solution to 100 ml. 

There is inevitably some doubt about the existence of octahedral as opposed to tetrahedral complexes in neutral solutions of FeCl3 since the peak at 2-25 A can be interpreted either in terms of tetrahedral coordination of Fe " by Cl (Fe-Cl, 2-25 A) or as the mean of 4 Fe-0 (2-07 A) and 2 Fe-Cl (2-30 A) in octahedral complexes of the type that exist in the crystalline hexahydrate (q.v.). On the other hand there seems to be no doubt about the existence of FeCl in dilute solutions containing excess Cl ions or of Fe2Cl6 molecules in non-aqueous solvents oflow dielectric constant such as methyl alcohol. 

IRON TRICHLORIDE (7705-08-0) FeCl3 6H20 Noncombustible solid. Very hygroscopic contact with moisture in air forms ferric chloride hexahydrate. Aqueous solution is highly acidic, precipitating hydroxide and phosphate salts, and, forming corrosive fumes. Violent reaction with strong... 

Iron(IIl) chloride (0.5m). Dissolve 135.2g iron(III) chloride hexahydrate, FeCl3 -6H20, in water, add a few millilitres concentrated hydrochloric acid if necessary, and dilute with water to 1 litre. If the solution turns dark, add more hydrochloric acid. 

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