Expert review

R. D. Harbison and W. E. Rinehart, eds.. Conclusions of the Expert Review Panel on Chromium Contaminated Soil in Hudson County, New Jersey, Industrial Health Foundation, Pittsburgh, Pa., 1990, p. 30. 

Several recent expert reviews and workshops have discussed the effects of endocrine disruption on wildlife and especially invertebrate species. These include the EU workshop on the impact of endocrine disrupters on human health and wildlife (Weybridge, 1996), the lEH workshop (Leicester, May 1997), the Environment Agency Consultative report (January 1998) and the Tyndall Forum at the Royal Institution (February 1998). They have concluded that endocrine disruption may have far-reaching adverse consequences for biodiversity and the sustainability of natural ecosystems. More comprehensive bioassay systems are required to identify and assess chemicals alleged to produce endocrine modulating effects. 

The enormous amount of research at the interface between physical and structural chemistry has been expertly reviewed recently by Schmalzried in a book about chemical kinetics of solids (Schmalzried 1995), dealing with matters such as morphology and reactions at evolving interfaces, oxidation specifically, internal reactions (such as internal oxidation), reactions under irradiation, etc. 

An international team of experts review the whole field of alkaloid chemistry This volume contains three special non recurrent reviews on bisindole alkaloids, the biosynthesis of terpertoid indole alkaloids, and on pharma -cologicalty interesting ar>d chemically useful alkaloids it covers the period January 1969 to Jur>e 1970. 50Spp til 00... 

Clinical trials are costly to conduct, and results are often critical to the commercial viability of a phytochemical product. Seemingly minor decisions, such as which measurement tool to use or a single entry criterion, can produce thousands of dollars in additional costs. Likewise, a great deal of time, effort and money can be saved by having experts review the study protocol to provide feedback regarding ways to improve efficiency, reduce subject burden and insure that the objectives are being met in the most scientifically sound and cost-effective manner possible. In particular, I recommend that an expert statistician is consulted regarding sample size and power and that the assumptions used in these calculations are reviewed carefully with one or more clinicians. It is not uncommon to see two studies with very similar objectives, which vary by two-fold in the number of subjects under study. Often this can be explained by differences in the assumptions employed in the sample size calculations. 

The public and the ethical industry are best served by decisions based on good science, adherence to high standards, and independent, expert review... If the industry starts with high quality science, effective analyses, and honest, responsive presentations, its regulatory problems will be few."... 

Vinarov, D.A. and Markley, J.L. (2005) High-throughput automated platform for nuclear magnetic resonance-based structural proteomics. Expert Review of Proteomics, 2 (1), 49-55. 

Arya, M., Shergill, I.S., Williamson, M., Gommersall, L., Arya, N., and Patel, H.R. 2005. Basic principles of real time quantitative PCR. Expert Review of Molecular Diagnostics 5, 209-219. 

Streatfield, S. 2005. Regulatory issues for plant-made pharmaceuticals and vaccines. Expert Review of Vaccines 4(4), 591-601. 

He, M. and Khan, F. 2005. Ribosome display next generation display technologies for production of antibodies in vitro. Expert Review of Proteomics 2(3), 421-430. 

A commissioned expert review, discussing a key topic of current interest, and referring to the References and Abstracts section. Reference numbers in brackets refer to item numbers from the References and Abstracts section. Where it has been necessary for completeness to cite sources outside the scope of the Rapra Abstracts database, these are listed at the end of the review, and cited in the text as a. 1, a.2, etc. 

Wolpert, C., Schimpf, R., Veltmann, C., Giustetto, C., Gaita, F. and Borggrefe, M. (2005) Clinical characteristics and treatment of short QT syndrome. Expert Review of Cardiovascular Therapy, 3, 611-617. 

We the editors send our warmest regards to all the authors who had to put up with our constant nagging and repeated demands on several rounds of revisions. To some authors, it may have caused some anxiety attacks, for which we apologise and also commend them profusely for their patience and hard work. Last, but not the least, both Carsten Ehrhardt and Kwang-Jin Kim appreciate the expert review and digestion for the in silico chapters extended by their mutual friend, Ian Haworth, Ph.D., at the University of Southern California - School of Pharmacy. Finally, we also realise that the book is a live being that constantly requires updates and mending, as the science moves forward. Therefore, we can hardly wait for the next edition for that reason. 

There has been only one change of author since last year. We welcome Dr C. Bedford as author of Reactions of Carboxylic, Phosphoric and Sulfonic Acids and their Derivatives. He replaces Dr W.J. Spillane, whose major contribution to the series, through provision of expert reviews since 1983, we wish to acknowledge. 

By following this two-tiered approach, a less expert reviewer will be able to follow the main ideas of your work, whereas an expert reviewer will be able to judge the intellectual merit of your proposal fully. 

Colman, P. M. (2005). Zanamivir an influenza vims neuraminidase inhihitor, Expert Review of... 

The documentation of procedures to be followed, including training outlines and manuals, are an important part of the validation evidence. Accompanying that documentation should be an expert review for appropriateness and a confirmatory observation to determine the degree to which those documented procedures reflect the reahties of the laboratory. 

II. Regulatory (or expert) review of plan Once the multitier validation plan has been developed it is possible to develop a preuse level of confidence by conferring with FDA representatives or experienced industry experts. While most FDA divisions... 

The written plan or SOP on vahdation should include the regulatory or expert review, identifying the approach as an appeal procedure to resolve issues relating to the three-tier system. 

Dr. Gold has served on the Panel of Expert Reviewers for the National Toxicology Program and on the boards of the Harvard Center for Risk Analysis and the Annapolis Center she was a member of the Harvard Risk Management Group and is at present a member of the Advisory Committee to the Director, National Center for Environmental Health, Centers for Disease Control and Prevention (CDC). She is among the most frequently cited scientists in her field and was awarded the Annapolis Center Prize for risk communication. 

Ranson, M. Mansoor, W. Jayson, G. Expert Review of Anticancer Therapy 2002, 2, 161-168. 

Lebens, M., Sun, J.B., Czerkinsky, C. and Holmgren, J. (2004) Current status and future prospects for a vaccine against schistosomiasis. Expert Review of Vaccines 3, 315-328. 

The IPCC has so far prepared five detailed reports (Houghton, Jenkins, and Ephraums, 1990 Watson, Zinyowera, and Moss, 1996 IPCC, 2001, 2005, 2007) as well as several special reports and technical papers. Griggs and Noguer (2002) have briefly reviewed the first volume of the Third IPCC Report (TIR) prepared by WG-I for the period June 1998-January 2001 with the participation of 122 leading authors and 515 experts. Four hundred and twenty experts reviewed the first volume and 23... 

Perico N, Ruggenenti P, Remuzzi G. Losartan in diabetic nephropathy. Expert Review of Cardiovascular Therapy 2004, 2, 473 -83. 

A large number of technical reviewers are acknowledged and thanked by both the editors and the authors for their expert reviews and many helpful suggestions and criticisms that greatly improved the quality of the book. 

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