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Excipient Functionality by Coprocessing

Piyush Gupta, Satish K. Nachaegari, and Arvind K. Bansal [Pg.109]

Department of Pharmaceutical Technology (Formulations), National Institute of Pharmaceutical Education and Research (NIPER), Punjab, India [Pg.109]

Stability Residual moisture content—adsorbed moisture on excipient surface protects drug from hydrolytic degradation [Pg.110]

Process ability Surface area, surface free energy, crystal defects, and deformation potential affect compressibility and machineability on high-speed tableting machines with reduced compression dwell times Particle size distribution and shape affect flow properties, efficiency of dry mixing process, and segregation potential Compressibility, flow ability, and dilution potential affect the choice of direct compression as a manufacturing process [Pg.110]

Performance Cohesive and adhesive properties, surface free energy, and water uptake behavior affect disintegration and dissolution behavior [Pg.110]


The spectrum of functionality modification can be substantially enlarged by the coprocessing or particle engineering of two or more existing excipients. Coprocessing involves interaction of two or more excipients at the subparticle level, aimed at... [Pg.114]


See other pages where Excipient Functionality by Coprocessing is mentioned: [Pg.109]    [Pg.111]    [Pg.113]    [Pg.115]    [Pg.117]    [Pg.119]    [Pg.123]    [Pg.125]    [Pg.109]    [Pg.111]    [Pg.113]    [Pg.115]    [Pg.117]    [Pg.119]    [Pg.123]    [Pg.125]    [Pg.109]    [Pg.111]    [Pg.113]    [Pg.115]    [Pg.117]    [Pg.119]    [Pg.123]    [Pg.125]    [Pg.109]    [Pg.111]    [Pg.113]    [Pg.115]    [Pg.117]    [Pg.119]    [Pg.123]    [Pg.125]    [Pg.109]    [Pg.119]    [Pg.109]    [Pg.119]    [Pg.123]    [Pg.123]    [Pg.113]    [Pg.178]    [Pg.113]    [Pg.538]   


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Coprocessing

Excipient

Excipient Functionality

Excipient function

Excipients

Excipients functions

Functional excipients

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