European standards understanding requirements

Obtaining European standards is the easy part understanding the requirements is another story Misapplication and/or misinterpretation are commonplace. 

The MIAME standard defines the minimum information investigators must report for a microarray experiment to be reproduced. The MAGE standard was born partially from MIAME, and the European Bioinformatics Institute used MIAME and MAGE to guide the development of ArrayEx-press, their public genomic data repository (34). Sample annotation lies at the heart of MIAME, underscoring the need to understand as completely as possible the experimental conditions that may influence the microarray data. Many journals that publish microarray data require the submission of MIAME-supportive microarray data to a public genomic data repository as a condition of publication. These typically include submission of protocols species, strains, and sex used for in vivo studies cell line name and culture conditions for in vitro studies, and other relevant information. 

The short term standard defined by the European Union (Direetive 2008/50/EC) (European Parliament, Council of the European Union 2008) for particulate matter smaller than 10 pm (PMio) is violated in many European cities (Querol et al. 2004 Van Dingenen et al. 2004), therefore the current air quality status of PMio is under investigation in many countries, in particular to understand the source terms of the particulate matter and to propose a catalogue of measures to avoid further exceeding of the limiting value. Eor a targeted reduction of PMio levels, detailed knowledge of sources and their respective contribution to the PM levels is required. 

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