Euler-Chelpin, Hans

Euler-Chelpin, Hans Karl August Simon von. Ibid., 4, 485-86 (1971). 

Euler-Chelpin, Hans Karl August Simon von (1873-1964) Swedish chemist who carried out a great deal of the earliest work on enzymes. He showed their optimum conditions for function, interaction with vitamins, inhibition by metallic ions and other substances, and the distinction between yeast saccharases and those occurring in the intestine. For his work on enzymes he shared the 1929 Nobel Prize in chemistry with Arthur Harden. 

Arthur Harden and Hans A. S. von Euler-Chelpin Chemistry Fermenting enzymes, fermentation of sugars... 

Ulf Svante von Euler (1905-1983) was born in Stockholm, Sweden, to a distinguished academic family. His father, Hans von Euler-Chelpin, received the 1929 Nobel Prize in chemistry his godfather, Svante Arrhenius, received the 1903 Nobel Prize in chemistry and his mother had a Ph.D. in botany. Von Euler received an M.D. from the Karolinska Institute in 1930, and then remained there his entire career (1930-1971). He received the 1970 Nobel Prize in medicine for his work on the chemical transmission of nerve impulses. 

Arthur Harden, Hans von Euler-Chelpin For their investigations on the fermentation of sugar and fermentative enzymes. ... 

Harden, Sir Arthur. (1865-1940). An English chemist who won the Nobel Prize in chemistry in 1929 along with Hans von-Euler-Chelpin. He discovered fermentation enzymes and demonstrated the structure of zymase. His fermentation work proved how inorganic phosphates speeded the process. Born in England, he received his doctorate in Germany. 

Henry Taube 1929 Arthur Harden, Hans von Euler-Chelpin... 

In 1929, the Nobel Prize in chemistry was shared by Arthur Harden and Hans von Euler-Chelpin (1873-1964) for their work, culminating... 

Arthur Harden and William J. Young (see chapter 1) showed three decades earlier that the fermentation enzyme in yeast is separable into a colloidal fraction ( zymase ) and a heat-stable, water-soluble fraction ( cozymase ). Tbe two fractions separately show no enzymatic activity. Warburg later demonstrated the activity of cozymase and, in 1936, nicotinic acid (niacin or vitamin Bj) was found to be its hydrolysis byproduct. In that year, Hans von Euler-Chelpin published the structure of nicotinamide adenosine dinucleotide (NAD ) and its phosphate derivative (NADP ) (see the structure below). Euler-Chelpin shared the 1929 Nobel Prize in chemistry with Arthur Harden for their independent studies on cozymase, seven years before publication of the NAD structure. In contrast to FMN and FAD, NAD, and NADP only transfer two electrons (H + 2e") at a time (see the structure below). 

Hans Karl August Simon von Euler-Chelpin (1873-1964)... 

Harden, Sir Arthur (1865-1940) British chemist who shared the 1929 Nobel Prize in chemistry with Hans Euler-Chelpin for their classic work on fermentation enzymes. Harden proved that living organisms were not necessary for fermentation and that the process could be inhibited if a factor was removed by dialysis. This was the enzyme. He also found that during fermentation, inorganic phosphate esterified into organic forms. 

Not given 1929 Hans K.A.S. von Euler-Chelpin/ Arthur Harden... 

Arthur Harden (UK) and Hans v. Euler-Chelpin (Germany)... 

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