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Ethylene teratogenicity

Toxicology. Dipropylene glycol methyl ether (DPGME) at very high concentrations causes narcosis in animals, and it is expected that severe exposure will produce the same effect in humans. Because the propylene glycol ethers are metabolized differently from the ethylene glycol ethers, they are not associated with potent teratogenic, spermatotoxic, or hematopoietic effects. ... [Pg.285]

Ethylene dichloride has been shown to alkylate DNA, and it is genotoxic in a variety of in vivo and in vitro assays. " It was not feto-toxic or teratogenic in rats, rabbits, or mice at doses that were not maternally toxic. "... [Pg.322]

Khera KS Ethylene thiourea Teratogenicity study in rats and rahhits. Teratology 7 243, 1973... [Pg.332]

Hanley TR Jr, et al Comparison of the teratogenic potential of inhaled ethylene glycol monomethyl ether in rats, mice and rabbits. Toxicol Appl Pharmacol 75 409-422, 1984... [Pg.447]

Horton VL, Sleet RB,John-GreeneJA, etal Developmental phase-specific and dose-related teratogenic effects of ethylene glycol monomethyl ether in CD-I mice. Toxicol Appl Pharmacol 80 108-118, 1985... [Pg.447]

Rao, K.S., Murray, J.S., Deacon, M.M., John, J.A., Calhoun, L.L. Young, J.T. (1980) Teratogenicity and reproduction studies in animals inhaling ethylene dichloride. In Ames, B.N., Infante, P. Reitz, R., eds, Ethylene Bichloride A Potential Health Risk (Banbury Report No. 5), Cold Spring Harbor, NY, CSH Press, pp. 149-166... [Pg.527]

Ethylene oxide is listed as a teratogen in the 1979 NIOSH subfile of RTECS (ref. 8le). [Pg.382]

La Borde, J.B. and C.A. Kimmel, "Teratogenicity of Ethylene Oxide Administered Intravenously to Mice," Toxicol Appl. Pharmacol. 56, 16-22 (1980). As cited in NIOSH ref. 76a. [Pg.451]

DOT CLASSIFICATION 6.1 Label Poison SAFETY PROFILE A poison by ingestion, inhalation, skin contact, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by inhalation. It can affect the nervous system, liver, spleen, and lungs. An experimental teratogen. Mutation data reported. A severe eye and mild skin irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Violent reaction with chlorosulfonic acid, ethylene diamine, sodium hydroxide. Reacts with water or steam to produce toxic and corrosive fumes. Potentially violent reaction with oxidizing materials. When heated to decomposition it emits highly toxic fumes of CT and phosgene. See also CHLORINATED HYDROCARBONS, 7M.IPHATIC. [Pg.622]

In animals, ethylene oxide has toxic effects on reproduction and is teratogenic, but the relevance of animal and epidemiological studies to occupational exposure of... [Pg.1299]

See other pages where Ethylene teratogenicity is mentioned: [Pg.361]    [Pg.361]    [Pg.192]    [Pg.192]    [Pg.557]    [Pg.464]    [Pg.190]    [Pg.927]    [Pg.324]    [Pg.327]    [Pg.180]    [Pg.146]    [Pg.361]    [Pg.361]    [Pg.464]    [Pg.244]    [Pg.372]    [Pg.381]    [Pg.447]    [Pg.295]    [Pg.70]    [Pg.204]    [Pg.1073]    [Pg.383]    [Pg.629]    [Pg.870]    [Pg.984]    [Pg.1188]    [Pg.1189]    [Pg.1248]    [Pg.146]    [Pg.3520]    [Pg.1519]    [Pg.898]    [Pg.1107]    [Pg.1263]    [Pg.2654]    [Pg.2666]    [Pg.386]    [Pg.192]    [Pg.192]   
See also in sourсe #XX -- [ Pg.399 , Pg.400 ]



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