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Estramustine

Estrazinol 2, 142 Estradiol I, 162 2, 136 Estradiol benzoate 162 Estradiol cypionate 1, 162 Estradiol dipropionate 1, 162 Estradiol hexabenzoate T, 162 Estradiol valerate 162 Estramustine 83... [Pg.267]

Bis(/3Estramustine phosphate p-[N-bis(/3phenyl-butyric acid Prednimustine... [Pg.1617]

Estradiol valerate Estramustine phosphate Estriol succinate Polyestradiol phosphate Estradiol-17/3... [Pg.1632]

CnH3 F204Si2) see Gemcitabine iV,0-bis(4-chlorobenzoyl)tyr amine (C22H17CI2NO5 4/859-56-7) see Bezafibrate bis(2-chloroethyl)amine (C4H9CI2N 334-22-5) see Cyclophosphamide Estramustine phosphate... [Pg.2309]

C13H1SCIN5O3 136522-32-2) see Abacavir Al-chloroformyl-bis(2-chloroethyl) amine (CgHjCl NO 2998-56-3) see Estramustine phosphate... [Pg.2329]

C23H3,Cl2N03 2998-57-4) see Estramustine phosphate (17P)-estra-l,3,5(10)-triene-3,17-diol dicyclopentane-propanoate... [Pg.2372]

CI3OP 10025-87-3) see Cyclophosphamide Estramustine phosphate Etopophos Ifosfamide Miltefosine Torasemide Vidarabine... [Pg.2435]

Li Y, Hong X, Hussain M, Sarkar SH, Li R, Sarkar FH. Gene expression profiling revealed novel molecular targets of docetaxel and estramustine combination treatment in prostate cancer cells. Mol Cancer Ther 2005 4 389-98. [Pg.164]

Estramustine, an oral drug, also inhibits microtubule assembly and has weak estrogenic activity at the estradiol hormone receptors of the cell. Approximately 75% of a dose of estramustine is absorbed.15 The terminal half-life ranges between 20 to 24 hours, with nonrenal excretion as the major route of elimination. This drug is used primarily for the treatment of prostate cancer, but its use is limited by the side effects, which include nausea and vomiting, diarrhea, thromboembolic events, and gynecomastia. [Pg.1288]

Chemotherapy, with docetaxel and prednisone or docetaxel and estramustine, improves survival in patients with hormone-refractory prostate cancer. Patients with hormone-refractory prostate cancer should be considered for entry into clinical trials investigating new therapies for prostate cancer. [Pg.1357]

Estramustine -inhibitor of microtubules -nausea and vomiting -headache -edema -impotence -gynecomastia -increases thromboembolic risk... [Pg.171]

The combination of estramustine 280 mg by mouth three times daily on days 1 to 5 and docetaxel 60 mg/m2 on day 2 of a 21-day cycle also improves survival in hormone-refractory metastatic prostate cancer. Estramustine causes a decrease in testosterone and a corresponding increase in estrogen, which results in an increase in thromboembolic events, gynecomastia, and decreased libido. [Pg.731]

Haukaas, S.A., Hoisater, P.A. and Kalland, T. (1982). In vitro and in vivo effects of diethylstilbestrol and estramustine phosphate (Estracyte) on the mutagen responsiveness of human peripheral blood lymphocytes. Prostate 3 405-414. [Pg.591]

Petrylak, D.P. et al., Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer, N. Engl. Med., 351,1513-1520, 2004. [Pg.455]

Alkyl sulfonates busulfan treosulfan aziridines ThioTEPA and TEPA methylmelamine altretamine N-mustards mechlorethamine, chlorambucil, phenylacetic acid mustard, melphalan, prednimustine, estramustine nitrosoureas tallimustine, tauromustine, lomustine/carmustine dacarbazine, temozolomide and mitozolomide... [Pg.113]

Reaction of bis(2-chloroethyl )amine with phosgene affords the corresponding carbamoyl chloride (J ). Acylation of estradiol (3) with this reagent leads to estramustine... [Pg.1133]

See other pages where Estramustine is mentioned: [Pg.372]    [Pg.83]    [Pg.84]    [Pg.257]    [Pg.267]    [Pg.237]    [Pg.578]    [Pg.579]    [Pg.1696]    [Pg.1698]    [Pg.53]    [Pg.416]    [Pg.784]    [Pg.2372]    [Pg.2434]    [Pg.151]    [Pg.151]    [Pg.1288]    [Pg.1368]    [Pg.50]    [Pg.50]    [Pg.50]    [Pg.50]    [Pg.50]    [Pg.51]    [Pg.183]    [Pg.602]    [Pg.111]    [Pg.1132]   
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