Estimated glomerular filtration rate

Within normal limits estimated glomerular filtration rate = 74 mL/minute... 

MDRD Formula for Estimating Glomerular Filtration Rate (from the Modification of Diet in Renal Disease Study)3... 

Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine A new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999 130 461 470. 

Goldberg TH, Finkelstein MS Difficulties in estimating glomerular filtration rate in the elderly. Arch Intern Med 1987 147 1430. [PMID 3453695]... 

Abbreviations BB, beta blocker BIS, bisoprolol BP, blood pressure EGFR, estimated glomerular filtration rate HCTZ, hydrochlorothiazide. 

Jonsson AS, Flodin M, Flansson LO, Larsson A. Estimated glomerular filtration rate (eGFR(CystC)) from serum cystatin C shows strong agreement with iohexol clearance in patients with low GFR. Scand J Clin Lab Invest. 2007 9 1 -9. 

Ishani A,GranditsGA,Grimm RH,Svendsen KH, Collins AJ, Prineas RJ, Neaton JD Association of single measurements of dipstick proteinuria, estimated glomerular filtration rate, and hematocrit with 25-year incidence ofend-stage renal disease in the multiple risk factor intervention trial. JAm Soc Nephrol 17 1444-1452,2006. 

S45 Rupe, C.O. and Cunningham, C.L. (1982). Creatinine test strip procedure for estimating glomerular filtration rates. Clin. Chem. 28, 1580, Abstr. 156. 

Coresh J, Astor BC, McQuillan G, Kusek J, Greene T, van-Lente F, et al. Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate. Am J Kidney Dis 2002 39 920-9. 

Schwartz Gj, Brion LP, Spitzer A. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children and adolescents. Pediatr Clin North Am 1987 34 571-590. 

Patients with hypertension may develop damage to either the renal tissue (parenchyma) or the renal arteries. Chronic kidney disease presents initially as microalbuminuria (30-299 mg albumin in a 24-hour urine collection) that can progress to macroalbuminuria and overt kidney failure. The rate of kidney function deterioration is accelerated when both hypertension and diabetes are present. Once patients have an estimated glomerular filtration rate (GFR) of less than 60 mL/m per minute or macroalbuminuria, they have chronic kidney disease, and the risk of cardiovascular disease and progression to severe chronic kidney disease increases. Strict BP control to a goal of less than 130/80 mm Hg can slow the decline in kidney function. This strict control often requires two or more antihypertensive agents. 

Urinary tract In 306 consecutive patients starting aminoglycoside therapy in an ITU-independent susceptibility factors for aminoglycoside-associated nephrotoxicity were a baseline estimated glomerular filtration rate (eGFR) under 60 mFminute/ 1.73 m, diabetes mellitus, treatment with other nephrotoxic drugs or iodinated contrast agents, and hypotension [5 ]. 

Urinary tract In 290 patients with chronic hepatitis B, of whom 145 had taken adefovir 10 mg/day, and 145 patients matched for age, sex, and baseline estimated glomerular filtration rate (eGFR), adefovir was a significant predictor of renal dysfunction (HR = 3.94) [7. ... 

The assessment of kidney function with estimated glomerular filtration rate (eGFR) using CKD-Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) formulas is key for correct and safe drug prescribing. 

Levey AS, Stevens LA, Schmid CH, et ak A new equation to estimate glomerular filtration rate. Aim Intern Med 2009 150 604-612. 

A retrospective review of 938 patients with stable renal insufficiency (estimated glomerular filtration rate or eGFR between 15 and 60 mL /min) who xmderwent contrast-enhanced CT were compared to a control group of 1164 patients with tire same GFR characteristics who underwent noncontrast CT. CIN developed in 6.1% and 5.8% of the patients in tire contrast enhanced CT group and noncontrast CT group respectively, with no statistical difference (p = 0.82) [27 ]. 

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