Essential Item Program

Documentation is essential to program planning and coordination, in addition to the obvious use for the summary of activities and results. Written communication becomes important for larger complex programs, especially when conducted under severe constraints on time and resources. Documentation can consist of some or all of the following items ... 

The years 1939-41 were a period of initial industrial mobilization, during which programs for the construction of badly needed facilities got under way and a start was made in procuring critical and essential items. This period was to reap the reward of the labors of the previous years, when so many blueprints for arsenals and plants had been drawn up and so many procurement plans had been made in the Chemical Warfare Service. 

The items in this list are essential to maintaining a well-designed incident investigation program. A high priority should be to promote reporting to learn from near miss incidents before a substantial loss occurs. 

At the Properties item Caption, replace the Forml with your form title choice. In this program I chose Datainput. As the essential data input of the program, this seemed a good choice for a title. By caption is simply meant a heading or a title. I don t know why the VB designers used such nomenclature here. I would simply have used the word Title. Oh well. 

Aseptic Assembly. The first interventions performed are those that prepare the equipment for the aseptic process. This entails the removal of sterilized materials and equipment items from the autoclave and transfer to the location where the aseptic processing activities will be performed. This is ordinarily followed by the assembly/preparation of the equipment for the process. Aseptic assembly in which sterilized parts are removed from protective materials, installed and adjusted in preparation for the aseptic process are perhaps the most potentially invasive of all of the activities which must be performed. The operator must be meticulous in their execution of these tasks to prevent the inadvertent contamination of product contact surfaces. Strict adherence to the principles of aseptic technique described earlier is essential. These interventions are a necessary part of every aseptic activity, and it is common to identify the first containers filled as they may be more indicative of potential problems with the aseptic assembly. For this reason, the validation program should include process simulations that include containers filled immediately after the set-up of the equipment. 

Periodic, scheduled facility safety inspections are essential in any operational area, especially where hazardous tasks are performed on a regular basis. Compliance with safety inspection requirements should not be difficult to accomplish since similar requirements should already exist in an established occupational safety program. The facility inspection encompasses all facets of daily operation and considers the human-machine interface a primary candidate area for potential mishaps. Frequent facility inspections are an excellent method of maintaining current awareness of facility conditions and how those conditions affect, or might affect, the safe operation of that facility. A system should be in place to ensure implementation of corrective actions and to track repetitive items. Results of inspections should be properly documented and accountability for discrepant items appropriately determined and assigned in order for the inspection process to be effective. If properly performed, the facility safety inspection is an excellent tool in the overall success of the system safety function. 

In a very successful metaphoric style, all items of the computer world that have to do with programs are called software, while all the rest (electronic parts, wires, input-output devices) are called hardware. Partly countering the intrinsic semantics of these two words, in the last years software has become much more expensive than hardware. Computer elaboration is a matter of switching between electronic zero and electronic one, and therefore on the hardware side computer speed depends on the speed at which the electronic status of a solid device can be modified. This response of electrons to an electric stimulus in turn is a matter of the electronic structure of the solid (see Section 6.2). This is a technical matter. On the software side, higher speed depends on a better organization of the code. Computer speed is anyway an essential variable in the development of computational theoretical chemistry [3]. 

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