Esophagus cancer

SAMMON A M (1998) Protease inhibitors and carcinoma of the esophagus. Cancer. 83 405-8. 

Mouth cancer Pharynx, larynx, esophagus cancer Prostate cancer Skin cancer... 

Huang Q, Stoner G, Resau J, Nick-ols J, Mirvish SS. 1992. Metabolism ofN-nitrosomethyl-amylamine by micro-somes from human and rat esophagus. Cancer Res. 52 3547-51... 

Harris CC. Autrup H. Stoner GD. et al. 1979. Metabolism of B[a]P. N-nitrosodimethylamine. and N-nitrosopyrrolidine and identification of the major carcinogen-DNA adducts formed in cultured human esophagus. Cancer Res 39 4401-4406. 

Introduced about 40 years ago, Fluorouracil 177 (5-fluorouracil, also called 5FU) is used for treatment of various types of cancer, including bowel, breast, stomach, and gullet (esophagus) cancer. Numerous methods of synthesis of 177 are reported. The 2-fluoroenals, -enones, and -enesters may serve as building blocks for the... 

Esophagus cancer Rectum cancer Colon cancer LarjTLX cancer Bronchus cancer Breast cancer Breast cancer... 

S. Huang, L. Wang, W. Chen, S. Feng, J. Lin, Z. Huang, G. Chen, B. Li, R. Chen, Potential of non-invasive esophagus cancer detection based on urine surface-enhanced Raman spectroscopy. Laser Phys. Lett. 11, 115604 (2014)... 

Since light absorption is limited in tissue penetration, PDT is suitable for the treatment of surface tumors like melanoma, or on the lining of internal organs such as the lungs or esophagus cancer. The technique is still limited to large tumors. 

Inhibition of Nitrosamine Formation. Nitrites can react with secondary amines and A/-substituted amides under the acidic conditions of the stomach to form /V-nitrosamines and A/-nitrosamides. These compounds are collectively called N-nitroso compounds. There is strong circumstantial evidence that in vivo A/-nitroso compounds production contributes to the etiology of cancer of the stomach (135,136), esophagus (136,137), and nasopharynx (136,138). Ascorbic acid consumption is negatively correlated with the incidence of these cancers, due to ascorbic acid inhibition of in vivo A/-nitroso compound formation (139). The concentration of A/-nitroso compounds formed in the stomach depends on the nitrate and nitrite intake. 

These symptoms may be indicative of complications of GERD such as Barrett s esophagus, esophageal strictures, or esophageal cancer. 

Radiation is carcinogenic. The frequency of death from cancer of the thyroid, breast, lung, esophagus, stomach, and bladder was higher in Japanese survivors of the atomic bomb than in nonexposed individuals, and carcinogenesis seems to be the primary latent effect of ionizing radiation. The minimal latent period of most cancers was <15 years and depended on an individual s age at exposure and site of cancer. The relation of radiation-induced cancers to low doses and the shape of the dose-response curve (linear or nonlinear), the existence of a threshold, and the influence of dose rate and exposure period have to be determined (Hobbs and McClellan 1986). 

Mirvish, S.S., Issenberg, P., and Sornson, H.C. Air water and ether-water distribution of TV-nitroso compounds implications for laboratory safety, analytic methodology, and carcinogenicity for the rat esophagus, nose, and liver, J. Nat Cancer Instil, 56(6) 1125-1129, 1976. 

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