Endocrine Pathology

Long-acting thyroid stimulator (LOTS) original name for the autoantibodies of Graves disease 

Thyroid tumors tend to be cold nodules on thyroid iodine 131 scans. 

Osteoporosis and osteitis fibrosa cystica Metastatic calcifications vi. Neurologic changes Secondary hyperparathyroidism a. Etiology 

Neuromuscular excitability and tetany Chvostek s and Trousseau s signs 

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The clinical course of the delayed neuro-endocrine toxicity and the typical manifestations with prevalence of neuro-endocrine pathology appears very similar in animal experiments and in real conditions in men. 

DeLellis RA, Tischlet AS. The dispetsed NE cell system. In Ko-vacs K, Asa SL, eds. Functional Endocrine Pathology. Oxford Blackwell Science 1998 529-549. 

Lloyd RV. Immunohistochemical localization of chromogranin in polypeptide hormone producing cells and tumors. In Lecha-go J, Kameya T, eds. Endocrine Pathology Update. Philadelphia Field and Wood 1990. 

Pesticides have a statistically reliable effect on children in zones where OCPs are intensively used (in the Salyansk region of Azerbaijan, the amount of OCPs introduced into humans exceeded public health standards by up to 7.7 times). Primary illness of the endocrine system increased 3.1 times in children up to age 15 (over a five year observation period) in disruptions in diet and metabolism, the nervous system, and the sensory and respiratory organs in increased frequency of illness (over five years) in children up to age 15 (an overall increase by 3.6 times, and by class of illness, from 2.2-7.6 times) in the prevalence of pathological disruptions according to data from medical examinations of children from 8-14 years (an overall increase by 2.3 times, and by class of illness by 2.0-8.4 times) in... 

It appears likely that the term "pathological intoxication" may be applied only to extremely acute cases, and that less acute examples of essentially the same disease exist without getting special notice. It is well known that the effect of alcohol on different individuals is often characteristic some become drowsy, some sad, some happy, some pugnacious. Pathological intoxication may occur in certain individuals, whose make-up predisposes to it, when they are in a particular metabolic and endocrine state. 

In practical veterinary the SC can be used in substitution therapy in case of different pathologies. The methods of making 3-D cell construction have been already invented and are applied for the substitution of large bone, skin, and cartilage defects. The transplantation of bone marrow stem cells is used in the case of animal oncology diseases. The methods of cell therapy with the usage of SC are approbated in the treatment of autoimmune and endocrine diseases of domestic animals. 

In a prospective study in 77 consecutive women with postmenopausal breast cancer scheduled to start endocrine treatment for breast cancer, using either tamoxifen or an aromatase inhibitor tamoxifen treatment significantly increased endometrial thickness and uterine volume after 3 months (24). In additional, tamoxifen induced endometrial cysts and polyps and increased the size of pre-existing fibroids. In contrast, aromatase inhibitors did not stimulate endometrial growth and were not associated with endometrial pathology. Furthermore, they reduced endometrial thickness and uterine volume in patients who had previously taken tamoxifen. 

The status of pathological mucopolysaccharides in amyloid, hyalin, granulation tissue, etc., in relation to D-glucuronic acid metabolism, is beyond the scope of this review. Likewise, the endocrine influence on myxedema fluid, the cock s comb, the sex skin of lower primates, chorionic tissue, etc., cannot be discussed here. 

Gorski JR, Muzi G, Weber LWD, et al. 1988b. Some endocrine and morphological aspects of the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicologic Pathology 16 313-320. 

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