Endocrine hypogonadism

Endocrine disorders (hypogonadism and pituitary, adrenal, and thyroid disorders)... 

Replacement Therapy. Testosterone and other androgens are administered as replacement therapy when the endogenous production of testosterone is impaired. Such conditions include removal of the testes (orchiectomy), various intrinsic forms of testicular failure (cryptorchidism, orchitis), and problems in the endocrine regulation of testosterone production, such as lack of LH production and other forms of hypogonadism.32,144... 

Considerable endocrine disorders may be present at times in cirrhosis patients. Progressive testicular atrophy with impotence and eunuchoidism (hypogonadism, abdominal baldness , Chvostek s habitus) can occur. Fully developed testicular atrophy appears regularly in haemochromatosis. 

Cundy, T., Butler, X, Bomford, A., Williams, R. Reversibility of hypo-gonatotrophic hypogonadism associated with genetic haemochromatosis. Clin. Endocrin. 1993 38 617-620... 

Therapeutic indications for androgens are deficient endocrine functions of the testes, such as hypogonadism. 

Many of the endocrine disorders that result in male infertility have been discussed earher in this chapter in the section on male reproductive abnormalities. Testosterone is essential for normal sperm development. Therefore, any disorder that results in hypogonadism (and hence low testosterone concentrations) results in infertility. Among the causes are both hypogonadotropic and hypergonadotropic hypogo-... 

In the eugonadal male with normal sperm analysis, no endocrine investigations are required. In the hypogonadal male, testosterone and the gonadotrophins should be measured First (Fig. 2). Causes of. subfertility in the male include ... 

Impaired endocrine function AD in most AD in most AD in most AD and hypogonadism in most... 

Seminara, S.B., Hayes, F., and Crowley, W.F. Jr. (1998) Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and kallmann s syndrome) pathophysiological and genetic considerations. Endocrine Revs., 19, 521-539. 

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