Gas chromatography enantioselective

N. A. Konig, "Enantioselective Gas Chromatography With Modified Cyclodextrins , Huethig, Heidelberg, 1991. 

Liu W, Gan JJ (2004) Determination of enantiomers of synthetic pyrethroids in water by solid phase microextraction - enantioselective gas chromatography. J Agric Food Chem 52 736-741... 

Konig WA, Fricke C, Saritas Y, Momeni B, Hohenfeld G, Adulteration or natural variability Enantioselective gas chromatography in purity control of essential o As, J High Resolut Chromatogr2Q i i—G, 1997. 

Konig WA, Hochmuth DH, Enantioselective gas chromatography in flavor and fragrance analysis Strategies for the identification of known and unknown plant volatiles J Chromatogr Sci. 42 423 39, 2004. 

W. A. Konig, Enantioselective Gas Chromatography with Modified Cyclodextrins, Hiilhig, Heidelberg 1991. 

Enantioselective gas chromatography can provide three quite different kinds of information (1) the amount of each enantiomer present in a food, determined as the enantiomeric purity or the enantiomer excess, and the separation factor a for each pair of enantiomers (2) enantiospecific sensory evaluation using gas chromatography-olfactometry (GC-O) and (3) data used as part of an authenticity determination. 

Ruderisch, A., Pfeiffer, J., and Schurig, V. (2003) Mixed Chiral Stationary Phase Containing Modified Resorcinarene and Beta-Cyclodextrin Selectors Bonded to a Polysiloxane for Enantioselective Gas Chromatography,/. Chromatogr. 994, 127-135. 

Ghanem, A. Ginatta, C. Jian, Z. Schurig, V. Chirasil-/7dex with a new Cl 1-spacer for enantioselective gas chromatography application to the kinetic resolution secondary alcohols catalyzed by lipase. Chromatographia 2003, Vol. 57, S-275-281. 

Despite the long recognition of chirality in POPs, it has only been fairly recently that studies of chiral POPs have been possible, after the introduction of analytical technology for stereoisomer separation by enantioselective gas chromatography (GC), high performance liquid... 

Wiberg, K. Letcher, R. Sandau, C. Duffe, J. Norstrom, R. Haglund, P. Bidleman, T. Enantioselective gas chromatography/mass spectrometry of methylsulfonyl PCBs with apph-cation to Arctic marine mammals Anal Chem. 1998, 70, 3845-3852. 

Because of the three asymmetric centers in the molecule there exist eight different stereoisomers. To identify the stereochemistry of wine lactone syntheses for the enantiomers were developed. On the basis of enantioselective gas chromatography the stereochemistry of wine lactone was in agreement with the 3S,3aS,7aR-enantiomer (72) for this stereoisomer a low odor threshold was determined (0.00002 ng/L air) ... 

The potency of enantioselective gas chromatography became apparent in the pharmacokinetic studies of flecainide [3] and two of its chiral metabolites as carried out by Fischer et al. (40). Trace amounts of these compounds in plasma samples were screened for enantiomeric discrimination. 

Although enantiomer separation of amino adds has always been a domain of chiral diamide phases such as Chirasil-val (1] or XE-60-L-val- S)-a-phenylethylamide [2], the development of hydrophobic cyclodextrm derivatives has affected even this field of applications of enantioselective gas chromatography. Octakis(3-O-butyryl-2,6-di-0-pentyI)-7-cyclodextrin [Lipodex E , (32) (see footnote on p. 115)] is highly selective for amino acid enantiomers. Since hydrogen bonding is not necessary for a determination of the enantiomers, some unusual amino adds can be separated that could not be resolved before, including p-amino adds, a-alkylated, and N-alkyl-ated amino adds. 

A. Mosandl, U. Hener, H.-G. Schmarr, M. Rautenschlein (1990) Chirospecific flavor analysis by means of enantioselective gas chromatography, coupled on-Une with isotope ratio mass spectrometry. 1. High Resol. Chromatogr. 13, 528-531... 

Konig, W.A., I. H. Hardt, B. Gehrcke, D.H. Hochmuth, H. Huhnerfuss, B. Pfaffen-berger, and G. Rimkus. 1994. Optically active reference compounds for environmental analysis obtained by preparative enantioselective gas chromatography. Angew. Chem. Int. Ed. Engl. 33 2085-2087. 

Ruderisch, A, J Pfeiffer and V Schurig (2003). Mixed chiral stationary phase containing modified resorcinarene and yS-cyclodextrin selectors bonded to a polysiloxane for enantioselective gas chromatography. Journal of Chromatography A, 994(2), 127-135. 

Konig WA (1989) Enantioselective gas chromatography with modified cyclomalto-oligosaccharides as chiral stationary phases. Carbohydrate Research 192 51-60. 

Enantioselective gas chromatography is applied for enantiomeric analysis in many different fields such as... 

Bicchi, C. Liberto, E. Cagliero, C. Cordero, C. Sgorbini, B. Rubiolo, P. Conventional and narrow bore short capillary columns with cyclodextrin derivatives as chiral selectors to speed-up enantioselective gas chromatography and enantioselective gas chromatography mass spectrometry analyses. J. Chromatogr. A, 2008, 1212, 114-123. 

Hochmuth, D.H. Koenig, W.A. Determination of the rotational energy barrier of planar-chiral cyclophanes using dynamic enantioselective gas chromatography and computer simulation. Liebigs Ann. 1996, 6, 947-951. 

Lehmann, D., A. Dietrich, U. Hener, and A. Mosandl, 1995. Stereoisomeric avour compounds LXX, 1-p-menthene 8 thiol Separation and sensory evaluation of the enantiomers by enantioselective gas chromatography/olfactometry. Pl tochenL nal., 6 255. 

Steroidal saponins are isolated from dried plant material including aerial parts, roots, and bark and are usually partitioned into a polar organic solvent before purification via reverse phase (RP) HPLC. The planar structure and stereochemistry of the isolated steroidal saponins is then typically determined using a combination of multistage mass spectrometry (MS"), ID and 2D NMR experiments, chemical degradation and derivatization, and enantioselective gas chromatography (GC). 

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