Embryological development

Primary immunodeficiency diseases (PIDs) are defects of the immune system that are due to genetic abnormalities or some failure in normal embryological development. They are usually apparent at birth or develop shortly thereafter. Approximately 70 PIDs have been described, including those specihc for humoral immunity (e.g., X-linked agammaglobulinemia, immune globulin [Ig] A dehciency), cellular immunity (e.g., DiGeorge s syndrome), or both (e.g., severe combined immunodehciency syndrome). 

Echinodermata or spiny-skinned animals (starfish, sea urchins, and sea cucumbers) are regarded as a highly advanced phylum. Their embryological development has been studied intensively. 

Embryological Development of Mutarotase and Sugar Transport in Kidney and Intestine... 

Timeyko, V.N. and Novikov, G.G. (1991). Influence of temperature on the utilisation of stored carbohydrates during the embryological development of Atlantic salmon (In Russian). Voprosy Ikhtiologii 31,851-859. 

The fetal warfarin syndrome involves neurological as well as bone abnormalities. Vitamin K-dependent carboxylase is expressed in different brain regions at different times during embryological development. 

PCF appears not to be necessary for life or for embryological development. However, this prostaglandin is required for the delivery of a fully developed baby. Knock-out mice that lack the PGF receptor were prepared by standard genetic techniques. These mice appeared norma , but when pregnancy came to the end of its term the baby mice were not ejected from the uterus the utems did not contract-If a cesarean birth was performed, the babies grew and developed normally otherwise, they died inside their mothers (Sugimoto et ttl., 1997). PGF has also been found to regulate the pressure of the eye (Abramovitz et ai, 1994). 

The transformation series runs in the embryological development from... 

The topic of teratogenesis as a disruption of the control of embryological development is covered later in this chapter. Safety screening requires evaluation of developmental and reproductive toxicity of the compounds of interest [5],... 

Embryological development is a highly conserved, highly regulated sequence of events in which many processes must be activated or deactivated... 

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