Electrospun-PLA fibres

Melt electrospun PLA sub-micron fibre mats with no residual solvent can be employed as filter media and tissue scaffolds preferred to those prepared by solution electrospinning processes, due to the elimination of possible... 

PLA Electrospun Nanocomposite Fibres witb Halloysite Nanotubes... 

PLA Electrospun Nanocomposite Fibres with Hydrojg apatite... 

In order to prepare PLA nanocomposites with highly dispersed cellulose nanocrystals and porous PLA-based scaffolds with enhanced mechanical properties and thermal stability, CNCs have been incorporated into PLA fibres by electrospinning method. Fibrous biocomposite mats consisting of PLA and CNCs have been electrospun from solvent or solvent mixtures such as l,l,l,3,3,3-hexafluoro-2-propanol (HFP), DMF/chloro-form and DMF/tetrahydrofuran (THF). The electrospun PLA/CNCs bionanocomposites have demonstrated rapid in vitro biodegradability and cytocompatible properties, and could be potentially suitable in tissue engineering. ... 

Similarly, AIT was incorporated in electrospun fibres at diverse concentrations. The study proved that the shape and diameter of fibres were modified with the concentration of AIT. At high concentrations, PLA fibres become thinner while the AIT appeared to be accumulated in spherical particles. The release of AIT was monitored as a function of the relative humidity (RH) and it was observed that humidity activates the release by accelerating the process and increasing its extent. ... 

Valente, T.A.M., Silva, D.M., Gomes, P.S., Fernandes, M.H., Santos, J.D., Sencadas, V., 2016. Effect of sterilization methods on electrospun poly(lactic acid) (PLA) fibre ahgnment for biomedical applications. ACS Appl. Mater. Interfaces 8,3241-3249. 

The transport properties of electrospun nylon 6 mats have also been investigated by scientists. It has been found that the concentration of the polymer solution affected the fibre diameter, pore size, Brunauer-Emmett-Teller surface area and gas transport properties of the mats. It was shown that the filtration efficiency of nylon 6 nanofilters is superior to that of a commericial high efficiency particulate air filter for 0.3 micrometre test particles. Researchers found that the pore size and pore size distribution of electrospun polylacticacid (PLA) membranes are strongly associated with fibre mass, fibre diameter and fibre length. 

H. J. (2012) Statistical design of experiments for electrospun poly(lactic acid) (PLA)/halloysite nanotube (HNX) composites in response to fibre diameter and... 

Finally, the mechanical properties of PLA-electrospun mats obtained by using different solvents were studied by Liao et al In particular, fibres obtained from a solution of PLA and chloroform (CHCI3) were prepared by using a collector disc with a centrifugal field of 1800 rpm. The experimental conditions used in this case, indicated with (a) in Table 6.4, are voltage 15 kV, flow-rate 0.25 mL h and distance between the needle and the cylinder 200 mm. Other samples, indicated with [h] in Table 6.4, were obtained from a PLA solution with a solvents mixture and a collector disc with centrifugal field 1800 rpm, flow-rate 0.25 mL h , 30 kV and distance between the needle and the cylinder 200 mm. From these results, it is worthwhile to note that the solvent and its evaporation rate strongly influence the PLA-electrospun fibres behaviour. The best results were obtained when a mix of tetrahydrofuran and chloroform was used. 

In general terms, biodegradable polyesters such as PLA, and poly (s-caprolactone) (PCL) are suitable choices for constructing nanofibrous scaffolds," by their good processability and mechanical properties. In fact, electrospun fibres of these polymers could replicate the physical dimensions and morphology of the major components in native ECM. On the other... 

Scanning electron micrographs of typical electrospun fibres fabricated from (A) polyglycolic acid, (B) PLGA, (C) PLA, (D) PLGA, (E) PLLA, and (F) PCL. Scale bars = 10 pm. 

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