Electrochemiluminescence system

Probably the most sensitive biosensor for rapid screening has been the ORIGIN electrochemiluminescence system (IGEN, Gaithersburg, MD). The primary reason for the ORIGIN S enhanced sensitivity is that it preconcentrates the target prior to the assay. Immunomagnetic beads are... 

Most electrochemiluminescent systems rapidly decay with time (cf. Fig. 6), even when strenuous efforts are made to exclude impurities and when applied voltages are minimal. Some unusual temporary increases in emission intensity with time have also been noted.63 These have not yet been satisfactorily explained. 

Radical 80 has been prepared as its perchlorate salt by anodic oxidation in ethyl acetate in the presence of hthium perchlorate. The reactivity toward nucleophiles of material so prepared was investigated nitrite and nitrate ions give 2-nitrodibenzo[l,4]dioxin although the mechanisms of the reactions are not clear. Pyridine gives 7V-(2-dibenzo[l,4]dioxinyl)pyridinium ion (84). Other nucleophiles acted as electron donors and largely reduced 80 back to the parent heterocycle they included amines, cyanide ion and water. In an earlier study, the reaction of 80 with water had been examined and the ultimate formation of catechol via dibenzo[l,4]dioxin-2,3-dione was inferred. The cation-radical (80) has been found to accelerate the anisylation of thianthrene cation-radical (Section lII,C,4,b) it has been found to participate in an electrochemiluminescence system with benzo-phenone involving phosphorescence of the latter in a fluid system, and it has been used in a study of relative diffusion coefficients of aromatic cations which shows that it is justified to equate voltammetric potentials for these species with formal thermodynamic redox potentials. The dibenzo[l,4]dioxin semiquinone 85 has been found to result from the alkaline autoxidation of catechol the same species may well be in-... 

Kim has reported a reaction of 178 with a,a -azobisbutyronitrile. Other reactions of 178 with radicals are the various reactions which occur in electrochemiluminescent systems. ... 

Thermodynamic redox properties have also been given for 198 in previously cited papers, and the rate of electron exchange between 198 and its parent heterocycle has been obtained by an electrochemical method the participation of 198 in electrochemiluminescent systems has been reported. ... 

The anion-radicals from 2,5-diphenyloxazole and similar substances are sufficiently persistent for use in various electrochemiluminescent systems. 

Several electrochemiluminescent systems have been described which involve 220.i -i - - - 2... 

Ultrasound influences multiphase systems such as the production of microemulsions. It is useful in electrosynthesis involving immiscible materials—this effect has been particularly exploited for several applications in environmental science. Ultrasound can also enhance electrochemiluminescence systems, and has been applied to many other aspects of electrochemistry, including the as yet unexplained benefits of pre-treating electrolyte solutions. It has even been proposed to enhance electrochemical cold-fusion . 

Several electrochemiluminescent systems have been described which involve... 

Kapturkiewicz A, Angulo G (2003) Extremely efficient electrochemiluminescence systems based on tris(2-phenylpyridine)iridium(iii). Dalton Trans 0(20) 3907-3913... 

Chen M, Wei X, Tu Y (2011) A luminol-based micro-flow-injection electrochemiluminescent system to determine reactive oxygen species. Talanta 85(3) 1304—1309. doi 10.1016/ j.talanta.2011.06.002... 

Gao Y, Xu Y, Han B, Li J, Xiang Q (2009) Sensitive determination of verticine and verticinone in Bulbus Fritillariae by ionic liquid assisted capillary electrophoresis-electrochemiluminescence system. Talanta 80(2) 448-453. doi 10.1016/j.talanta. 2009.07.012... 

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