Elastin-like polymers

Arias FJ, Reboto V, Martin S et al (2006) Tailored recombinant elastin-like polymers for advanced biomedical and nano(bio)technological applications. Biotechnol Lett 28 687-695... 

Some polymers have been purified on the basis of their physicochemical properties. For example, silk-like polymers have been purified by taking advantage of their low solubility in aqueous medium (13). Elastin-like polymers (ELPs) have been purified by temperature cycling above and below their inverse temperature transition (Tt) (14). This technique has been extended to produce an ELP-tag that can be used to purify a number of recombinant proteins by temperature cycling, which may be faster and less expensive than affinity chromatography (15). 

Alonso M, Reboto V, Guiscardo L, Mate V, Rodriguez Cabello JC. 2001. Novel photoresponsive p phenylazobenzene derivative of an elastin like polymer with en hanced control of azobenzene content and without pH sensitiveness. Macromolecules 34(23) 8072 8077. 

Rodriguez CabeUo JC, Alonso M, Guiscardo L, Reboto V, Girotti A. 2002. Amplified photoresponse of a p phenylazobenzene derivative of an elastin like polymer by alpha cyclodextrin the amplified delta T t mechanism. Adv Mater 14(16) 1151 1154. 

Herrero-Venrell, R. Rincon, A.C. Alonso, M. Reboto, V. Molina-Martinez, I.T. Rodriguez-Cabello, J.C. Self-assembled particles of an elastin-like polymer as vehicles for controlled drug release. J. Contr. 

This overview will mainly focus on those polymers found in natural structural proteins, particularly the silk-elastin-like polymers (SELPs) of recombinant DNA technology origin. 

Rodriguez-CabeUo, J.C., Prieto, S., Regueta, J.etaL (2007) Biofunctional design of elastin-like polymers for advanced applications in nanobiotechnology. Journal of Biomaterials Science-Polymer Edition, 18, 269-286. 

Haider, M., Leung, V., Ferrari, F. et al. (2005) Molecular engineering of silk-elastin-like polymers for matrix-mediated gene delivery Biosynthesis and characterization. Molecular Pharmaceutics, 2, 139-150. 

Machado, R., Azevedo-Silva, J., Correia, C. et al. (2013) High level expression and facile purification of recombinant silk-elastin-like polymers in auto induction shake flask cultures. AMB Express, doi 10.1186/2191-0855-3-11... 

Hybrid Nanofibres via Self-Assembly of Elastin-Like Polymers Templating Cadmium... 

In this context, Fahmi et al. reported a unique approach to the generation of semiconductor cadmium selenide (CdSe) nanofibres prepared via self-assembled elastin-like polymers (ELPs) [(VPGVG)2(VPGEG)(VPGVG)2]i5 in aqueous solution at room temperature. The biomolecule cruitrols the size and size distribution of the CdSe nanoparticles and directs the structure fomiaticHi into hybrid nanofibres [34]. 

Alvarez-Rodriguez, R. Alonso, M. Girotti, A. Reboto, V. Rodriguez-CabeUo, J. C. One-pot synthesis of pH and temperature sensitive gold clusters mediated by a recombinant elastin-like polymer. Eur. Polym. J. 2010, 46, 643-650. 

Elastin-like recombinamer is a new and more suitable definition that has replaced the former term elastin-like polymer (ELP) [1]. It is an explicit term that can be specifically associated with this new type of macromolecule and that is... 

Rodriguez-Cabello JC, Prieto S, Arias FJ, Reguera J, Ribeiro A (2006) Nanobiotech-nological approach to engineered biomaterial design the example of elastin-like polymers. Nanomedicine 1 267-80... 

Reguera J, Fahmi A, Moriaity P, Girotti A, Rodriguez-Cabello JC (2004) Nanopore formation by self-assembly of the model genetically engineered elastin-like polymer... 

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