Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Effector T cell

A distinct population of effector T cells that promote tissue inflammation has been described without suppressive functions [9]. This population is termed as Th9 cells and exerts IL-9 and IL-10 secretion capacities. IL-4 and TGF-(I promotes an IL-9-producing subset, Th9 cells, which have roles in mucus production and tissue inflammation [100,101]. [Pg.31]

Fig. 4. Regulatory T-cell functions suppression of DCs that support the generation of effector T cells suppression of ThI, Th2, and ThI 7 cells suppression of allergen-specific IgE and induction of lgG4, IgA, or both suppression of mast cells, basophils, and eosinophils interaction with resident tissue cells and remodeling, and suppression of effectorT-cell migration to tissues. [Pg.32]

Murphy TL, Murphy KM, Weaver CT Interleukin-17-producing CD4+ effector T cells develop via a lineage distinct from the T-helper type 1 and 2 lineages. Nat Immunol 2005 6 1123-1132. [Pg.41]

W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK IL-4 inhibits TGF-p-induced Foxp3+ T cells and, together with TGF-p, generates IL-9+ IL-10+ Foxp3- effector T cells. Nat Immunol 2008 9 1347-1355. [Pg.41]

CCR1 Effector T cells RANTES/CCL5 MIP-loc/CCL3 MCP-2/CCL8 MCP-3/CCL7 Yes Inhibition... [Pg.60]

CCR2 Effector T cells MCP-1/CCL2 MCP-2/CCL8 MCP-3/CCL7 MCP-4/CCL13 Yes ND... [Pg.60]

CCR5 Effector T cells RANTES/CCL5 Yes Inhibition... [Pg.60]

CCR8 Effector T cells (Th2) I-309/CCL1 Yes Partial inhibition... [Pg.61]

CCR1, CCR5, and CXCR3 and the Recruitment of Monocyte/ Macrophage Cells and Effector T Cells... [Pg.144]

With regard to the specific accumulation of effector T cells in the inflamed RA joints, several papers have documented that T cells in the joints of individuals with RA preferentially express CCR5 (36-38). Furthermore, RA (39) and CIA are thought to be a T helper 1 (Thl)-driven diseases (12,40), and expression of CCR5 is considered to be the hallmark of Thl differentiation, both in... [Pg.169]

Fig. 3. The role of FKN/CX3R1 in inducing atherosclerosis may involve two mechanisms. The first is the release of soluble FKN through cleavage of membrane-expressed FKN by TNF-alpha converting enzyme (TACE). Soluble FKN is then able to attract circulating monocytes and effector T cells expressing CX3CR1. The second mechanism is that of firm adhesion of circulating cells to membrane-bound FKN. Fig. 3. The role of FKN/CX3R1 in inducing atherosclerosis may involve two mechanisms. The first is the release of soluble FKN through cleavage of membrane-expressed FKN by TNF-alpha converting enzyme (TACE). Soluble FKN is then able to attract circulating monocytes and effector T cells expressing CX3CR1. The second mechanism is that of firm adhesion of circulating cells to membrane-bound FKN.
The development of effector T cells following activation by antigen-presenting cells also requires the interaction of another receptor-ligand pair. CD40 molecules on antigen-presenting cells are required to bind... [Pg.353]

Yoshikawa T, Okada N, Oda A et al (2008) Nanoparticles built by self-assembly of am phiphilic poly(y-glutamic acid) can deliver antigens to antigen-presenting cells with high efficiency Anew tumor-vaccine carrier for eliciting effector T cells. Vaccine 26 1303-1313... [Pg.63]

See other pages where Effector T cell is mentioned: [Pg.23]    [Pg.26]    [Pg.29]    [Pg.29]    [Pg.87]    [Pg.235]    [Pg.60]    [Pg.60]    [Pg.60]    [Pg.60]    [Pg.60]    [Pg.108]    [Pg.109]    [Pg.115]    [Pg.141]    [Pg.169]    [Pg.306]    [Pg.325]    [Pg.40]    [Pg.134]    [Pg.475]    [Pg.548]    [Pg.181]    [Pg.2]    [Pg.3]    [Pg.8]    [Pg.9]    [Pg.17]    [Pg.21]    [Pg.24]    [Pg.30]    [Pg.30]    [Pg.31]    [Pg.32]   
See also in sourсe #XX -- [ Pg.284 ]



SEARCH



Effector

Effector cells

© 2024 chempedia.info