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Effector mechanisms

Humoral immunity depends on soluble, noncellular effector mechanisms of the immune system. These include defensins and complement components (proteins of the innate immune system) and antibodies (products of the adaptive immune system). They are capable of reacting with foreign substances (e.g., bacteria and viruses) to produce detoxification and elimination. [Pg.605]

While cells of the innate immune system can combat invading microbes autonomously, their effector mechanisms are also used and greatly enforced by the... [Pg.614]

The OP group of receptois share common effector mechanisms. All receptois couple via pertussis toxin-sensitive Go and Gi proteins leading to (i) inhibition of adenylate cyclase (ii) reduction of Ca2+ currents via diverse Ca2+ channels (hi) activation of inward rectifying K+ channels. In addition, the majority of these receptors cause the activation of phospholipase A2 (PLA2), phospholipase C 3 (PLC 3), phospholipase D2 and of MAP (mitogen-activated protein) kinase (Table 3). [Pg.905]

Gene Therapeutic Strategies that Act via Host Immune Effector Mechanisms.283... [Pg.265]

Table 21.2 The four opioid receptors with transmitters and drugs acting on the various receptors together with the effector mechanisms and the effects of receptor activation for each receptor... Table 21.2 The four opioid receptors with transmitters and drugs acting on the various receptors together with the effector mechanisms and the effects of receptor activation for each receptor...
Effector mechanism G-protein opens K+ channel G-protein opens K+ channel G-protein closes Ca channel G-protein opens K+ channel... [Pg.468]

Else, K.J. and Grencis, R.K. (1996) Antibody-independent effector mechanisms in resistance to the intestinal nematode parasite Trichuris muris. Infection and Immunity 64, 2950-2954. [Pg.368]

Drapier,J.C., Wietzerbin, J. and Hibbs, J.B. Jr (1988) Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. European Journal of Immunology 18,1587-1592. [Pg.398]

Volume 345. G Protein Pathways (Part C Effector Mechanisms)... [Pg.32]

Ferrant, J.L. et al., The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of immune challenge, Internal Immunol., 16, 1583, 2004. [Pg.139]

Effector Mechanisms Antibody-Mediated Versus Cell-Mediated Damage.425... [Pg.423]

EFFECTOR MECHANISMS ANTIBODY-MEDIATED VERSUS CELL-MEDIATED DAMAGE... [Pg.425]


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See also in sourсe #XX -- [ Pg.133 , Pg.243 ]




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