Drugs polymers, medication

Brannon-Pepas L. Polymers in Controlled Drug Delivery, Medical Device and Diagnosis Industry. Los Angeles, CA A Canon Communications LLC, 1998. 

J. Lahann, D. Klee, and H. HOcker. CVD-polymerization of a functionalized poly(p-xylylene). a generally applicable method for the immobilization of drugs on medical implants Materialwiss. Werkstofflech., 30 763-766,1999. S. Y. Park, J. Blackwell, S. N. Chvalun, A. A. Nikolaev, K. A. MaUyan, A. V. Pebalk, and I. E. Kardash. The structure of poly(cyano-p-xylylene). Polymer, 41(8) 2937-2945, April 2000. 

Lahann J, Klee D, Hocker H. CVD-polymer-ization of a functionalized poly(p-xylylene). A generally applicable method for the immobilization of drugs on medical implants. Materi-alwiss Werkstofftech 1999 30 763-6. 

These results open the exciting possibility of using degradable, tyrosine-derived polymers as "custom-designed" antigen delivery devices. On the other hand, our results indicate that the immunological properties of tyrosine-derived polymers will have to be carefully evaluated before such polymers can be considered for use as drug delivery systems or medical implants. 

While this book is focused on drug delivery, the value of biodegradable polymers is not limited to this field. Biodegradable polymers will be useful in other areas of medical therapeutics, such as sutures and bone plates and other types of prostheses. The polymers will also be useful in nonmedical fields, for disposable plastics, bottles, diapers and many other entities. 

FMC designs one such water-soluble coating for timed-release medications — Aquacoat ECD, a 30% by weight aqueous dispersion of ethylcellulose. This polymer is used to coat drug-layered beads that are delivered using gelatin capsules... 

Microspheres made of various polymers biodegradable to nonharm-ful compounds that could be metabolized and/or removed from organisms found many applications in medicine as carriers of drugs or other bioactive compounds [1 ]. Besides chemical composition there are also other properties of microspheres that are of primary importance to their medical applications. In particular, average diameters and diameter distributions illustrated in Table 1 based on data published in [5] are the relationship between the diameters of microspheres and their localization in various cells and tissues of the human body. 

Polymer-based biomaterials are becoming increasingly important, whether they are used as medical supplies (pipes, catheters, bags), prostheses, or dental materials, or in a pharmaceutical context as drug conjugates [4, 7, 158-160], protein conjugates [6, 158, 159, 161], synthetic vectors [12, 14, 18, 162, 163], or as immuno-adjuvants [164, 165]. 

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