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Drug metabolizing enzymes polymorphisms

Table 1 Test probe drags for human phenotyping of human drug-metabolizing enzyme polymorphisms... Table 1 Test probe drags for human phenotyping of human drug-metabolizing enzyme polymorphisms...
Nebert, D.W., R.A. McKinnon, and A. Puga. 1996. Human drug-metabolizing enzyme polymorphisms Effects on risk of toxicity and cancer. DNA Cell Biol. 15(4) 273-280. [Pg.222]

Su HI, Sammel MD, Velders L, Horn M, Stankiewicz C, Matro J, Gracia CR, Green J, DeMichele A. Association of cyclophosphamide drug-metabolizing enzyme polymorphisms and chemotherapy-related ovarian failure in breast cancer survivors. Fertil Steril 2010 94(2) 645-54. [Pg.641]

Polymorphic metabolism Genetically determined rates of metabolism (fast vs. slow) by selected isozymes of cytochrome P-450 drug-metabolizing enzymes. [Pg.1574]

Nebert DW. Polymorphisms in drug-metabolizing enzymes what is their clinical relevance and why do they exist Am J Hum Genet 1997 60 265-271. [Pg.9]

It has now been established that genetic polymorphisms in drug metabolizing enzymes such as the cytochrome P450s (CYP) and the phase II enzyme, thiopu-rine methyltransferase, are responsible for inter-individual variability in response and adverse reactions [12, 13]. However, at the present time, the impact of poly-... [Pg.179]

Tanaka E. Update genetic polymorphism of drug metabolizing enzymes in humans. J Clin Pharm Ther 1999 24 323-329. [Pg.278]

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See also in sourсe #XX -- [ Pg.89 ]



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Drug metabolism enzymes

Drug metabolism polymorphisms

Drug-metabolizing enzymes

Drugs, polymorphism

Enzymes drugs

Metabolic enzymes

Metabolic polymorphisms

Metabolism enzymes

Metabolizing enzymes

Polymorphic drug metabolizing enzymes

Polymorphic drugs

Polymorphic metabolic enzymes

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