Drug delivery system biomedical modification

V. J. Stella, T. J. Mikkelson, and J. D. Pipkin, Pro-drugs The control of drug delivery via bioreversible chemical modification, in Drug Delivery Systems Characteristics and Biomedical Applications (R. L. Ju-liano, ed.), Oxford University Press, New York, 1980,... 

Starch in its native or modified form, has been subjected to extensive study over the past 50 years. Early interest in starch was associated with the food and paper industry, textile manufacture, and pharmacolog) . With the increased interest of biomedical and pharmaceutical research in biodegradable polymers as matrices for controlled drug delivery systems, impressive activities on the modification of natural polymers to meet growing needs have been reported (Hag et al, 1990 Kost and Shefer, 1990 Shefer et al, 1992 Trimnell et al, 1982 Vandenbossche et al, 1992 Visavarungroj et al, 1990). 

Abstract Polysaccharides based nanomaterials have diverse applications in biomedical research. This chapter covers one of the major achievements in modification of polysaccharides using microwave irradiation and cationization methods. Additionally chapter focused on mucoadhesive polysaccharides and its recent advancement in nano drug delivery system. Applications such as gene transfection, bone regeneration and vaccine delivery are also separately discussed. 

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