DoTS classification, ADRs

U.S. Department of Transportation classification flammable Hquid, hazard label 3.3 DOT/UN /Na shipping number 2521, flammable Hquid. Transport by sea IMDG-code class 3.3, p. 3333, emergency sheet 3—06. Transport by rail and road RID/ADR class 3 Rn 301-31c. 

In 2003, a system of classification was proposed by Aronson and Femer based on dose-relatedness, time course and susceptibility this is known as DoTS. The main ways in which ADRs may be classified within each of these three categories is given below ... 

If suitable estimates of risk are available, it may be possible to draw three-dimensional DoTS diagrams of the probability of an ADR occurring in sub-groups over time and as a function of dose. When this is not possible, qualitative classification may still be useful, as shown by the following examples ... 

Material safety data sheets should list information which permits proper classification of material. A broad range of transportation data for specific materials is included in the Database of Antiblocking, Release, and Slip Agents. Transportation information in the database includes UN Risk Phrases, UN Safety Phrases, DOT Hazard Class, UN/NA, ADR/RID Class, ICAO/IATA Class, and IMDG Class which are required for transportation by air, water and land. 

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