Diphenyl propane

Acetone also reacts with diphenylamine, in the presence of acid, to form a variety of condition-dependent products (5). Excess amine and a small amount of strong acid catalyst at 100—150°C give 2,2-[4,4 -(dianilino)diphenyl]-propane [2980-26-9] (6). With a large amount of hydrochloric acid at 250°C in the presence of excess diphenylamine, the main product is 9,9-dimethylacridan [6267-02-3]. 

Enby 6 is an example of a stereospecific elimination reaction of an alkyl halide in which the transition state requires die proton and bromide ion that are lost to be in an anti orientation with respect to each odier. The diastereomeric threo- and e/ytAra-l-bromo-1,2-diphenyl-propanes undergo )3-elimination to produce stereoisomeric products. Enby 7 is an example of a pyrolytic elimination requiring a syn orientation of die proton that is removed and the nitrogen atom of the amine oxide group. The elimination proceeds through a cyclic transition state in which the proton is transferred to die oxygen of die amine oxide group. 

DieKeto- undEnol-Formen von l,3-Dioxo-2-methyl- 1,3-diphenyl-propan liefern ver-schiedene Reduktionsprodukte4 ... 

Diphenyl-1,3-propandiol wird dagegen mit Titan(III)-chlorid/Lithiumalanat zu ei-nem Gemisch aus 12°/0 cis- und 49% trans- ,2-DiphenyI-cyclopropanJ 20% 1,3-Diphe-nyl-propanol, 15% 1,3-Diphenyl-propan und 5% trans-1,3-Diphenyl-propen (Gesamt-ausbeute der Cyclopropan-Verbindungen 40% d.Th.) reduziert3 ... 

Phenyl-3-aryl-acrylnitrile werden durch Benzylalkohol in Kalilauge mit mittleren Ausbeuten zu den entsprechenden 2-Phenyl-3-aryl-propansaure-nitrilen redu-ziert1 (als Ausnahme erhalt man aus 2,3-Diphenyl-2-acrylnitril 2,3-Diphenyl-propan-sdure 70% d.Th.)1 ... 

Zur Reduktion von Harnsaure und seinen N-Alkyl-Derivaten s. S. 597 Auch 2,3-Dihydro-1,4-diazepinium-Salze werden in Athanol/Perchlorsaure an Kupfer im wesentlichen zu 1,4-Diazepanen reduziert. Wahrend beim 1,4-Diphenyl-Derivat hauptsachlich das Ringsystem erhalten bleibt, erhalt man aus dem 5,7-Diphenyl-Derivat unter Ringspaltung 1,2-Diamino-athan, 3-Oxo-l,3-diphenyl-propan und Chalkon3 ... 

Nur eine Carbonyl-Gruppe wird bei der Hydrodimerisierung von 1,3-Dioxo- 1,3-diphenyl-propan an Quecksilber reduziert [90% d.Th. 1,6-Dioxo-l,6-diphenyl-hexandiol-(3,4)]9-, analog verhalt sich 3,5-Dioxo-l,l-dimethyl-cyclohexan (Dimedon)10 ... 

Die Reduktion von Benzil liefert bei Gegenwart von Methylchlorid, -bromid, -jodid oder -tosylat als Hauptprodukt 2-Methoxy-J-oxo-1,2-diphenyl-propan neben cis- und trans-1,2- Dimethoxy-1,2- diphenyl-dthylen ... 

Fig. 16.6 The 1,3-diphenyl propane skeleton of flavonoids and the numbering system for flavonoids. Three structural features optimise the radical scavenging properties of a flavonoid (i) an orto-dihydroxy structure of the B-ring (catechol) (ii) 2,3 double bond in conjugation with a 4-oxo group (iii) 3- and 5-hydroxy groups (Bors and Saran, 1987).

Recently, the thermal decomposition of diaryl alkanes such as dibenzyl and 1,3-diphenyl propane has been studied by Sato and coworkers (13), Collins and coworkers (14). These compounds were confirmed to be decomposed to alkyl benzenes gradually as a function of carbon chain length. 

The condensation products (1 1) of pentane-2,4-dione and 1,3-diphenyl-propane-1,3-dione with thiosemicarbazide, 4-methylthiosemicarbazide, and aminoguanidinium nitrate were formed (86KGS128 87ZOB584 90-KGS1260) as the cyclic isomers 78, which sometimes readily underwent dehydration to the corresponding pyrazoles. 

The reaction of concentrated sulfuric acid with 2,2-dimethyl-1,1-diphenyl-propan-l-ol produced in high yield the )3-sultone 42. ... 

In contrast to the ubiquitous distribution of flavonoids hydroxylated at C-3 or C-4 of their heterocyclic rings, the unsubstituted flavans (2-phenylchromans) are more rarely found. The flavans co-occur with chalcones, flavanones, flavan-3,4-diols, flavonols, and 1,3-diphenyl-propanes. 

Analog gelingt es, Nitro-methan mit ( )-l, 2-Diphenyl-1 -nitro-ethen in Gegenwart von Kaliumfluorid/Kaliumsulfinylfluorid zu 1,3-Dinitro-1,2-diphenyl-propan umzusetzen3 ... 

R =R2 I] LI] Xn-O R-=h.r2 = ch, H l lN R2 R = R- = CH3 Na/( Ha C) a CH—OH/T H F 20-25 , 12 hj dann Hydrolyse 3-Amino-l-anilino-l, 3-diphenyl-propan 3-Amino- I-anillno-1-(4-methyl-phenyl)-1-phenyl-propan 3-Amino-l-(4-methyl-anilino) -3- (4-methyl-phenyl)- 1-phenyl-propan 91 88 91 3 3 3... 

Amino-pentan 5-Amino-nonan 2-Amino-1,3-diphenyl-propan... 

The crude product was purifled by silica gel column chromatography using pentane/diethyl ether (6 1) as eluent to yield 3.43 g (9.23 mmol, 81%) of (45,55)-2-(5-methyl-2-phenyl-4,5-dihydro-oxazol-4-yl)-l,3-diphenyl-propan-2-ol as a white foam. 

The flask was filled with (4S,55)-2-(5-methyl-2-phenyl4,5-dihydro-oxazol4-yl)-l,3-diphenyl-propan-2-ol (337 mg) and 15 mL of dry and degassed pentane. The solution was cooled to —78 °C using a dry ice/acetone bath. Under these conditions the alcohol partially precipitated. 

Moramide-Intermediate, 2-methyl-3-morpholino-l, 1-diphenyl-propane-carboxylic acid. 

Such a repeat unit can be modelled by considering the conformational characteristics of the fragment molecules, diphenyl carbonate (DPC) and 2,2 diphenyl propane (DPP), shown in Figs. 55 and 56, respectively. 

Diphenyl-l-propene-3-one gives (depending on the ratio ketone silane acid) 1,3-diphenyl-l-propanone (126) (1 1 10) and 1,3-diphenyl-propane (127) (1 3 10), respectively85. ... 

OF I-BROMO-1,2-DIPHENYL-PROPANE TO PRODUCE THE (Z) STEREOISOMER AND O THE (E) STEREOISOMER OF I, 2-diphenyl-I-propene. Test yourself on the concepts in this figure at OrganicChemistryNow. 

Reactions the E2 Reaction 9.2 Mechanism and Stereochemistry of the E2 Elimination Reactions of the Diastereomers of l-Bromo- 1,2-Diphenyl-Propane to Produce the (Z) Stereoisomer and the ( ) Stereoisomer of 1.2-Diphenyl-l-Propene (page 318) Mechanisms in Motion E2 Mechanism (page 317)... 

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