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Oxazole, dihydro

Oxazole, 2,5-dihydro-4-methoxy-synthesis, 6, 228 Oxazole, dihydro-2-methylene-reactions, 6, 215... [Pg.727]

Similar alkylations may be effected on oxygen. l-(2-Chloroethyl)imidazolidin-2-one (312) when treated with potassium hydroxide or sodium hydride underwent ring closure to the tetrahydroimidazo[2,l-6]oxazole (313) (57JA5276). This approach can be used for the preparation of bicyclic hydantoins and the corresponding dihydro derivatives of (313) using the mesylate of (312) and NaH (77JHC5U, 79JMC1030). [Pg.139]

Thieno[3,4-d]oxazole-3a(4H)-carboxylic acid, dihydro-2-methyl-synthesis, 6, 1020 Thieno[2,3-d Joxazoles synthesis, 6, 990 Thieno[3,2-g]pteridine structure, 3, 284 lH-Thieno[3,4-c]pyran-2-ones synthesis, 4, 1032 Thienopyrazines synthesis, 4, 1022-1024 Thieno[2,3-6]pyrazines, 4, 1023 electrophilic substitution, 4, 1024 Thieno[3,4-6]pyrazines, 4, 1024 Thieno[3,4-c]pyrazole, 4,6-dihydro-3-hydroxy-carbamates... [Pg.879]

The gold complex, generated in situ from bis(4-isocyanocyclohexyl)gold(I) tetrafluoroborate and (A)-A-methyl-,V-[2-(dialkylamino)ethyl]-l-[(5)-r,2-bis(diphenylphosphino)ferrocenyl]eth-ylamine, is an effective catalyst for the aldol reaction of various aldehydes with methyl iso-cyanoacetate to give the trans- and cw-4,5-dihydro-l,3-oxazoles. Depending on the aldehyde, the transjeis product ratio ranges from 84 16 to 100 0, and the ee of the main diastereomer is between 72 and 97%26. [Pg.583]

Under inversion of the configuration at sulfur, enantiomerically pure 4,5-dihydro-2-[(7 )-sulfinylmethyl)]oxazoles (e.g 2) are obtained from metalaled 4,5-dihydrooxazoles and (-)-menthyl (5,)-4-methylbenzenesulfinate31. [Pg.607]

Metalation of 4,5-dihydro-2-[(7 )-sulfinylmethyl]oxazoles (e.g., 2) with butyllithium at -90 C and reaction of the chiral azaenolates with aldehydes furnishes the hydroxyalkylated sulfinylox-azole derivatives 3 which are desulfurized to give the 4,5-dihydro-2-(2-hydroxyalkyl)oxazoles 4. The corresponding 3-hydroxy acids 5 are obtained by acidic hydrolysis in 60-85% overall yield and 26-53% ee31. [Pg.608]

Oxo-2,3-dihydro-(benzo-l,3-oxazole) werden durch Lithiumalanat zu den entsprechenden 2-Methylamino-phenolen aufgespalten. Aus 2-Oxo-2,3-dihydro-(benzo-1,3-oxazol) selbst erhalt man2-Methylamino-phenolzu 57% d.Th.11. 2-Oxo-3-chlorme-... [Pg.132]

Methyl-2-phenyl-4-athoxycarbonyl-l,5-dihydro-l,3-oxazol wird je nach Menge Li-thiumalanat entweder selektiv zum Alkohol reduziert oder man erhalt unter Ringspaltung 2-Benzylamino-3-hydroxy-butandiol-(1,3) (s. S. 347). [Pg.214]

Phenylacetylamino-2-methyl-propanol5 Zu einer Losung von 0,5 g (2,46 mMol) 5-Oxo-4,4-dimethyl-2-benzyl-4,5-dihydro-1,3-oxazol in einem Gemisch von 15 ml THF, Athanol und Wasser (1 1 1) werden unter Riihren in kleinen Portionen 0,05 g (1,3 mMol) Natriumboranat gegeben. Man laBt 20 Stdn. bei 20° stehen, siiuert an, cngt ein, extrahiert mit Diathylather, trocknet, entfernt die Solventien i.Vak. und kristallisiert den Riickstand aus Diathylather Ausbeute 0,47 g (91% d.Th.) F 75-76°. [Pg.228]

Analog erhalt man aus 5-Oxo-2-phenyl-4,5-dihydro-1,3-oxazol 2-Benzoylamino-athanol5 (88% d.Th.) und mit Lithiumalanat aus 5-Oxo-4-methyl-2-benzyliden-2,5-dihydro-1,3-oxazol 2-Phenylacetylamino-propanol (30% d.Th.)6. Calciumboranat reduziert 5-Oxo-2-phenyl-4-benzyliden-4,5-dihydro-1,3-oxazol zu oc-Benzoylamino-zimtal-kohol1. [Pg.228]

Diphenyl-4,5-dihydro-l,2-oxazol —> cis-3-Phcnyl-2-benzyl-aziridin 31% d.Th. [Pg.380]

Cyclische 0,N-Acetale vom Typ der 1,3-Oxazolidine und 2,5-Dihydro-l,3-oxazole werden durch Lithiumalanat7 und Natriumboranat8,9 zu 2-Amino-alkoholen reduziert. Aus 3-Methyl-2-phenyl-l,3-oxazolidin wird z.B. mit Natriumboranat 2-(N-Methyl-N-benzyl-amino)-athanol (74% d.Th) erhalten8 ... [Pg.436]

Symmetrisch substituierte 1,3,4-Oxadiazole liefern dagegen die Tetrahydro-1,3,4-oxadiazole, wahrend 5(2)-Phenyl-2(5)-naphthyl-(2)-l,3-oxazole nur zu 5(2)-Phenyl-2(5)-naphthyl-( 1 )-2,3-dihydro-1,3-oxazolen reduziert werden1 ... [Pg.591]

Bis-[ ( benzo-1,3-oxazol) -yl-(2)-thio]- 343 Bis-[1,4- (bzw. 3,4]-dihydro-naphthy[-(2)-oxy]- 588 Bis-[dimethylamino]- 345 Bis-[4-dimethyIamino-phenyl]- 346 Bis-[4-hydroxy-phenyl]-(2-carboxy-phenyl)- 167 Bis-[4-methoxy-phenyl]-dideutero- 346 Bis-[4-methyl-phenyl]-Bis-f 2-methyl-thiiranyl-(2)]- 570 Bis-[naphthyl-(2)-oxy]- 588 Bis-[naphthyl-(2)-thio]-... [Pg.909]

Methylamino-4,5-dihydro-(3,4l6-tri-0-acetyl-1l2-dideoxy-a-D-glucopyranoso)[2,1 -cfl-1,3-oxazole... [Pg.146]


See other pages where Oxazole, dihydro is mentioned: [Pg.727]    [Pg.727]    [Pg.727]    [Pg.727]    [Pg.728]    [Pg.727]    [Pg.727]    [Pg.727]    [Pg.727]    [Pg.728]    [Pg.4]    [Pg.726]    [Pg.727]    [Pg.778]    [Pg.20]    [Pg.96]    [Pg.584]    [Pg.608]    [Pg.662]    [Pg.1029]    [Pg.133]    [Pg.205]    [Pg.347]    [Pg.347]    [Pg.347]    [Pg.377]    [Pg.380]    [Pg.896]    [Pg.931]    [Pg.931]   
See also in sourсe #XX -- [ Pg.746 ]




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3-Formyl-2,3-dihydro- 1,3-oxazole

4.5- Dihydro-3- -oxazol-2-ones

Alkenes to 4,5-Dihydro-l,3-oxazoles

Dihydro- 1,3-oxazoles

Dihydro- 1,3-oxazoles

Olefins to 4,5-Dihydro-l,3-oxazoles

Oxazole, 3-acetyl-2,3-dihydro-2,2-dimethylphotochemistry

Oxazole, 4,5-dihydro-2-methyl-5-phenyl

Oxazoles, 2,5-dihydro-5-trifluoromethyl

Oxazoles, 2-alkyl-4,5«dihydro

Oxazoles, 2-alkyl-4,5«dihydro preparation

Oxazoles, 5-methylene-4,5-dihydro

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