Dimyristoyl-glycero-3-phosphocholine

Supported lipid bilayers on planar silicon substrates have been formed using S-layer protein from B. coagulans E38/vl and from B. sphaericus CCM 2177 as support onto which l,2-dimyristoyl-OT-glycero-3-phosphocholine (DMPC) (pure or mixtures with 30% cholesterol) or DPPC bilayers were deposited by the Langmuir-Blodgett-technique (Pig. 

Fig. 6 Structure of membrane components (a) dioctadecyldimethylammonium bromide, (b) 1,2-dimyristoyl, s7i-glycero-3-phosphocholine (DMPC), (c) 1,2-dilauroyl, S7i-glycero-3-phospho-choline (DLPC), (d) dicetyl phosphate (DCP)...

The lipids l,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipal-mitoyl-sn-glycero-3-phosphocholine (DPPC), and l,2-dilauroyl-5 -glycero-3-phosphocholine (DLPC), were obtained from Avanti Polar Lipids (Alabaster, AL) and used without further purification. Three types of samples were investigated ... 

Dimyristoyl-sn-glycero-3-phosphocholine monohydrate (dimyristoyl-L-a-lecithin)... 

Figure 8-6 (A) Molecular packing of 2,3-dimyristoyl-D-glycero-l-phosphocholine dihydrate. The two molecules in the asymmetric unit are labeled 1 and 2. The position of the water molecules is indicated either by W1-W4 or by small open circles. Hydrogen bonds are represented by dotted lines. From Pascher et al.66 (B) Two-dimensional "orthorhombic" arrangement of hydrocarbon chains in a crystalline alkane. The a-b plane corresponds to the plane of the bilayer surface the long axes of the acyl chains project from the page. From Cameron et al.67...

In addition to the long-chain fatty acid molecules described above, a large number of studies have appeared that use IRRAS to study phospholipid monolayers as models of biomembrane interfaces. Mitchell and Dluhy [26] reported the first IRRAS spectra of 1,2-distearoyl-5 -glycero-3-phosphocholine (DSPC), l,2-dimyristoyl-i -glycero-3-phosphocholine (DMPC), and 1,2-di-palmitoyl-,v/ -glycero-3-phosphocholine (DPPC) monolayers at the air-water... 

An example of how the procedure works is shown in Figure 18.5. The peptide in this example is MSI-103, which has been labeled with 19F at the four positions indicated in Figure 18.5a. Four different peptides were synthesized where a single amino acid (Ala-7, Ile-9, Ala-10, or Ile-13) was replaced with CF3-Phg. For each label a 19F NMR spectrum is recorded (see Figure 18.5a) in this example, spectra are from MSI-103 in DMPC (1,2-dimyristoyl-OT-glycero-3-phosphocholine) at a peptide-to-lipid molar ratio (P/L) = 1 400,... 

Figure 2.9 In situ STM imaging of l,2-dimyristoyl-sr)-glycero-3-phosphocholine (DMPC) lipid membranes. Molecular structures of the membrane constituents (a) DM PC (b) cholesterol, (c) DM PC...

Figure 181. Effect of membrane components on the leakage of 5-fluorouracil from liposomes during storage at 4°C. O, LW (PC/PS/CH 7 4 5) A, LUV (MC/PS/CH 7 4 5) O, MLV (PC/PS/CH 7 4 5). LW, Large unilamellar vesicle, PC, l,2-dipalmitoyl-sn-glycero-3-phosphocholine monohydrate, PS, dipalmitoyl-DL-C phosphatidyl-L-serine, CH, cholesterol, MC, l,2-dimyristoyl-sn-glycero-3-phosphocholine monohydrate, MLV, multilamellar vesicle. (Reproduced from Ref. 717 with permission.)...

El Khoury ED, Patra D. Ionic liquid expedites partition of curcumin into solid gel phase but discourages partition into liquid crystalline phase of l,2-dimyristoyl-sn-glycero-3-phosphocholine liposomes. JPhys Chem B. 117(33) (2013) 9699-9708. 

Champeil, MoUer, 2000). Some lipid/detergent mixtures have been used in nuclear magnetic resonance (NMR) and crystallization experiments (Seddon, Cumow, Booth, 2004) in structural and functional studies of the extremely light-sensitive G protein-coupled receptor (GPCR), rhodopsin, Reeves et al. used a mixture of the lipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine and the detergent 3-[(3-cholamidopropyl)-dimethylammonio]- -propane-sulfonate (CHAPS) (Reeves, Hwa, Khorana, 1999). 

Choleth-30 Cocamide DEA Coco-betaine Cocodimethylammonium-3-sulfopropylbetaine C12-13 pareth-23 Cl 2-14 pareth-11 Cl 2-14 pareth-23 Cl 2-15 pareth-10 Cl 2-15 pareth-15 Cl 2-15 pareth-20 Cl 3-15 pareth-20 C12-15 pareth-2 phosphate C12-15 pareth-8 phosphate C12-15 pareth-10 phosphate 2-Decyl-1 -tetradecanol 1,2-Dicaproyl-sn-glycero(3) phosphatidylcholine Dihydrocholeth-30 1,2-Dilauroyl-sn-glycero(3) phosphocholine 1,2-Dimyristoyl-sn-glycero(3)... 

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