10.10- diiodo-2,8-dimethyl

Imidazole, 4,5-dibromo-l-methyl-synthesis, S, 399 Imidazole, 4,5-di-t-butyl-synthesis, S, 483 X-ray diffraction, S, 350 Imidazole, 4,5-dichloro-chlorination, S, 398 synthesis, S, 398, 473 Imidazole, 4-(3,4-dichlorophenyl)-nitration, 5, 433 Imidazole, 4,5-dicyano-hydrolysis, S, 435-436 synthesis, S, 461, 472, 487 Imidazole, 4,5-dicyano-1-vinyl-synthesis, S, 387 Imidazole, 4,5-dihydro-mass spectra, 5, 360 Imidazole, 4-(dihydroxybutyl)-synthesis, S, 484 Imidazole, 4,5-diiodo-nitration, S, 396 synthesis, S, 400 Imidazole, 2,4-diiodo-5-methyl-iodination, S, 400 Imidazole, 1,2-dimethyl-anions... 

The crude iodinated acid was then dissolved in 500 ml of 95% alcohol, 10 g of dimethyl-aminoethanol was added, the solution was decolorized with activated charcoal and filtered at 70°C. After keeping the filtrate for several hours at 5°C, the heavy crystalline precipitate which formed was collected by filtration and washed with acetone. The mother liquors were concentrated to 150 ml and cooled to give a second crop which was further purified by recrystallization from 50 ml of 95% alcohol. In this way a total of 36.0 g of dimethyl-aminoethanol salt of dextro-/3-(3,5-diiodo-4-hydroxy)-o-phenylpropionic acid, MP 151° to 153°C, was obtained. The melting point of the dimethylaminoethanol salt of unresolved /3-(3,5-diiodo-4-hydroxy)-o-phenylpropionic acid was 142° to 144°C. 

M Industrial Chemical Products Div., St. Paul MN 55144-1000 DIBF, 5,7-diiodo-3-butoxy-6-fluorone (H-Nu 470), Spectra Group, Ltd., Maumee, OH 43537 OPPI, 4-octyloxyphenyl-phenyliodonium hexafluoroantimonate, G. E. Silicones, Waterford, NY 12188 and DIDMA, N,N-dimethyl-2,6-... 

Similarly, the two remaining perdeuterated analogues (CF3) Ge(CD3)4- (n = 2 and 3) form on treating bis(trifluoromethyl)diiodo- and tris(trifluoromethyl)iodo-germane, respectively, with dimethyl-dg cadmium (equations 9 and 10). 

The formation of cyclopropane by reduction of 1,3-dibromopropane was discovered in 1887. Dissolving metals, in particular zinc dust in ethanol, were employed as an electron source [88], Electrochemical reduction in dimethyl-formamide at a mercury cathode has been found to give good yields of cyclopropane [89, 90], 1,3-dibromo, 1,3-diiodo and l-chloro-3-iodopropane all give greater than 90 % yield of cyclopropane, the other product being propene. 

The present procedure is the most convenient method for preparation of mono- or diiodo derivatives from various poly-alkylbenzenes in high yields.1 2 Thus 5-i-butyl-1,3-dimethyl-benzene gives 4-<-butyl-2,6-dimethyliodobenzene in 90% yield and 4 - - buty I -1,2 - d imet hy 1 benzene gives 5-<-butyl-2,3-dimethyl-iodobenzene in 81% yield. 5- -Butyl-l,2,3-trimethylbenzene,... 

Fig. 39 Micrograph of polymerized uniform submicrostructure with 9 p.m line width and 50 xm line spacing. The structure was written by two-photon initiated electron-transfer free radical polymerization of diacrylate monomer Sartomer SR 349 at 775 nm via direct excitation of dye 5,7-diiodo-3-butoxy-6-fluorone(H-Nu 470) for (A) and dye 3 for (B) in the presence of Ar,Ar-dimethyl-2,6-diisopropylaniline...

The third known method of synthesis of the heterocycles 82 is exemplified by the preparation of 4,4-diiodo-l-oxa-4-telluracyclohexane 84 on heating bis(2-iodoethyl)ether with powdered tellurium (45JCS11). It has an analogy in the synthesis of dimethyl tellurium diiodide from methyl iodide and elemental tellurium (20JCS86), but is characterized by a rather low yield (10-13%) of product 84 because of partial decomposition of the initial oxide under the reaction conditions. When bis(2-chloroethyl)ether and Nal were used instead of bis(2-iodoethyl)ether and the reaction was... 

Azaborines have received a little attention in recent years, particularly 1,2,3-diazaborines (67) [75ACS(B)1036 76MI2 84MI1] (Scheme 58). Bromine in pyridine converted 5-ethyl-1,2-dimethyl-1,2-dihydro-1,2,3-borazine into a mixture of 4- and 6-monobromo derivatives, and the 4,6-dibromo compound. With iodine monochloride the 4-iodo or 4,6-diiodo products formed, depending on the mole ratio of iodine monochloride to substrate [75ACS(B)461]. 

The reaction of trimethylstannylsodium with two geminal dihalides, 6,6-dichloro-5,5-dimethyl-1-hexene and 6,6-diiodo-5,5-dimethyl-l-hexene, gave evidence of a single electron transfer pathway. An initial electron transfer from MetSn- to the geminal dihalides leads to the haloradical (X ), which then serves as the precursor to all the reactions and products detailed in Scheme 37195. 

Disubstitution product 107 was obtained in the reaction of l,3-diiodo-2,2-dimethyl-propane (106) with 27b (equation 78). The monosubstitution product is not an intermediate in this process157. These results are in agreement with a fast intramolecular ET to the a C—I bond of the monosubstituted radical-anion intermediate. 

The above approaches can be extended to 1,2-carboranes in which the BH vertices are substituted with alkyl groups <1996101235, 1996JA70>. The 9- and 12-boron vertices are the furthest from the carbon atoms in 1,2-carborane 7. Methyl substitution of 7 at these positions is accomplished by iodine substitution to form 9,12-diiodo-l,2-carborane 13 then treatment with alkyl Grignard reagent in the presence of a palladium catalyst affords 9,12-Me2-l,2-carborane 14, which can be deprotonated at the carbon vertices in the same manner as the parent 7. Using the same strategy to prepare cyclic trimer 5, dimethyl 14 is deprotonated and treated with mercuric acetate to form 5-hexamethyl-[9]-mercuracarborand-3 15 in 60% yield (Equation 1). 

SYNS DB 136 KETONE, 3,5-DIIODO-4-HYDROXYPHENYL 2.5-DIMETHYL-3-FURYL... 

DIIODO-4-HYDROXYPHENYL2,5-DIMETHYL-3-FURYL KETONE see DNF450... 

KETONE, DIETHYLAMINO(7,8,9,10-TETRAHYDRO-ll-6H-CYCLOHEPTA(b)QUINOLINYL) see TCOlOO KETONE, 3,5-DIIODO-4-HYDROXYPHENYL 2,5-DIMETHYL-3-FURYL see DNF450 KETONE, 3,5-DIIODO-4-HYDROXYPHENYL 2-ETHYL-3-BENZOFURANYL see E1D200 KETONE, 3,5-DIIODO-4-HYDROXYPHENYL 5-ETHYL-2-FURYL see EID250 KETONE, 3,5-DIIODO-4-HYDROXYPHENYL 2-FURYL see DNF500 KETONE, DIMETHYL see ABC750 KETONE, 5-DIMETHYLAMINO-3-INDOLYL PHENYL see DOU700... 

The 2,4-disubstituted derivatives of the aforementioned 3-metallacyclobutanones allow for cis and trans isomers, much as for cyclobutanone and cyclobutane. It is found that the diphenyl species [Pt CHPhC(0)CHPh (PPh3)2] is synthesized with predominantly cis stereochemistry. This is consistent with stereochemical expectations—however, disconcertingly, there are no examples of disubstituted cyclobutanes (or derivatives) for which the enthalpy of formation of both the cis and trans isomers are both known to confirm this expectation. Gibbs free energy differences have been determined for the dimethyl , dichloro, dibromo and diiodo ° species, again in the expected order °. Indeed, the only case where the trans isomer is known to be more stable than the cis is the enigmatic bis-phenylsulfonyl species for which no explanation has been offered ... 

Diboroles have been routinely analyzed by electron impact mass spectrometry. The method has been used to confirm only molecular masses when 2,3-dihydro-l,3-thiaboroles <19980M2379, 19990M1821> and 2-(2,2-dimethyl-propylidene)-4,5-diethyl-l,3-diiodo-2,3-dihydro-177-l,3-diborole 22 <2002ZN1125> were measured. When the molecular masses of other 2,3-dihydro-l/7-l,3-diboroles, 1,3-azaborolidines, 2,3-dihydro-l//-l, 3-stannaboroles, and... 

Bayer and Siebert tried to exchange methyl for iodine in 2-(2,2-dimethyl-propylidene)-4,5-diethyl-l,3-diiodo-2,3-dihydro-17/-l,3-diborole 22 by reacting with trimethylaluminium in pentane at -15°C <2002ZN1125>. However, due to the instability of the 1,3-dimethyl derivative 40, it was detected only by H NMR spectroscopy before rearranging into nido-Gt carboranes 41 and 42, as well as to polymeric materials (Scheme 2). 

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