Digestion simulated gastric

Fu, T.J., Abbott, U. And Hatzos, C., Digestibility of food allergens and non-allergenic proteins in simulated gastric and intestinal fluids — a comparative study. J. Agric. Food Chem., 50, 7154, 2002. 

Diaz-Perales, A., Blanco, C., Sanchez-Monge, R., Varela, J., Carrillo, T., and Salcedo, G. 2003. Analysis of avocado allergen (Prs a 1) IgE-binding peptides generated by simulated gastric fluid digestion. J Allergy Clin Immunol 112 1002-1007. 

Sequential Enzymatic Extractions for the Evaluation of the Bioaccessibility of Metals in Foodstuffs Some attention has been paid to the analysis of enzymatic digests of foodstuffs in the quest for molecular information to contribute to the knowledge of the bioavailability of some elements. Sequential enzymolyses in simulated gastric and gastrointestinal juice were proposed for an estimation of bioavailability of heavy metal species from meat [46] and cocoa samples [47, 48]. The soluble fractions of the stomach and upper intestinal... 

TABLE 5 Parameters of In Vitro Digestion in Artificial Stomach When Simulating Gastric Conditions of Adult after Intake of Glass of Milk... 

A second approach is to subject the food to a simulated gastric or gastrointestinal digestion using purified peptic and/or pancreatic enzymes with subsequent measurement of the soluble iron released by the digestion (10-13). Advantages of in vitro methods include 1. their low cost and speed, 2. their reduced... 

A further series of experiments assessed the stability of the conjugates to the two major sets of digestive enzymes commonly present in the human digestive tract simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). For each of the incubations, the rate of degradation of the conjugate was measured over 24 hours by LC-MS/MS. 

Korjagin, V., R. Herman, P. Hunst, et al. 2002. In Vitro Simulated Gastric Fluid Digestibility of Microbially Derived Cry34Abl Protein Lab Project Number 010111. Unpublished study prepared hy Dow AgroSciences LLC. 95 p. 

Hoebler, C., Lecannu, G., Belleville, C., Devaux, M.F., Popineau, Y., and Barry, J.L. 2002. Development of an in vitro system simulating bucco-gastric digestion to assess the physical and chemical changes in food. Int J Food Sci Nutr 53(5) 389-402. 

Yvon, M., Beucher, S., Scanff, P.,Thirouin, S., and Pelissier, J. P. (1992), In vitro simulation of gastric digestion of milk proteins Comparison between in vitro and in vivo data, J. Agric. Food Chem., 40, 239-244. 

The duodenum is the shortest part of the small intestine, where most chemical digestion occurs. The duodenum releases secretin, a hormone, which suppresses gastric acid. Cholecystokinin, a hormone, is released by the duodenum that simulates flow of bile from the gallbladder into the duodenum. Bile (produced by the liver), trypsin, chymotrypsin, lipase, and amylase (all produced by the pancreas) digest carbohydrates, protein, and fat in preparation for absorption in the small intestine. The duodenum connects the stomach to the jejunum. The jejunum is the second division of the small intestine and connects the duodenum to the ileum. The ileum is the end of the small intestine. 

In addition, DalTErta et al. described the stability of D3G and two zearalenone conjugates upon digestion by application of an in vitro assay that simulated human digestion. In particular, the salivary step (5 min), the gastric step (120 min) and the duodenal step (120 min) were mimicked, performing various sequential enzymatic treatments. 

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