Diethylenetriamine pentaacetic

Metals may also be linked through an oxygen or nitrogen atom to form a stable metal complex without a carbon-metal bond. These include metal complexes of ethylenediamine tetraacetate (EDTA), diethylenetriamine pentaacetate (DTPA), or ethylenediamine tetramethylphosphonate (EDTMP). Metalloid compounds include antimonyl gluconate and bismuth salicylate. 

Brechbiel, M. W., Beitzel, P. M., and Gansow, O. A., Purification of p-nitroben-zyl C-functionalized diethylenetriamine pentaacetic acids for clinical applications using anion-exchange chromatography, J. Chromatogr A, 771, 63,1997. 

Materials. Egg phosphatidylcholine (PC), bovine brain phosphatidylserine (PS) were obtained from Avanti Polar Lipids Inc. (Birmingham, AL) and cholesterol was from Sigma (St. Louis, MO). Ganglioside GMj, bovine, was obtained from Calbiochem (San Diego, CA). Diethylenetriamine pentaacetic acid distearylamide complex (DPTA-SA) was synthesized according to ref. 17 and nlIn-DTPA-SA was prepared as described (7). This lipophilic radiolabel is not transferred to the serum components from liposomes (unpublished data), nor is it rapidly metabolized in vivo (7). The synthesis of N-(glutaryl)phosphatidylethanolamine(NGPE) has been described (18). Dipalmitoyl deoxyfluorouridine(dpFUdR) was synthesized as described (24). 

Singh et al. (2006) also used cycloaddition to prepare carbon nanotubes containing indium labeled diethylenetriamine pentaacetic acid (DTPA) derivatives (Figure 15.17). In the initial modification, a SWNT was derivatized to contain a primary amine at the end of a short PEG spacer. The resultant water-soluble nanotube then was reacted with DTPA to create a metal chelating group at the end of the chain. Subsequent loading of the chelate with mIn created a radionuclide-SWNT complex for in vivo biodistribution studies. 

Gd Magnevist [Gd(III)(DTPA)(H20)]2 DTPA = diethylenetriamine pentaacetic acid MRI contrast agent... 

Chan, H-K., Daviskas, E., Eberl, S., Robinson, M., Bautovich, G., and Young, I.H., Deposition of aqueous aerosol of technetium-99m diethylenetriamine pentaacetic acid generated and delivered by a novel system (AERx) in healthy subjects, Eur. J. Nucl. Med., 26 320-327 (1999). 

DCTA 1,2-diaminocyclohexane tetraacetic acid DBP dibutyl phosphoric acid DTP A diethylenetriamine pentaacetic acid DEHPA di-2-ethylhexyl phosphoric acid... 

AAS = atomic absorption spectrometry DPTA = diethylenetriamine pentaacetic acid HNO3 = nitric acid ICP-AES = inductively coupled plasma-atomic emission spectroscopy Ni = nickel NIOSH = National Institute for Occupational Safety and Health... 

EDTA, ethylenediamine tetraacetic acid NTA, nitrilotriacetic acid HEEDTA, hydroxy-ethylethylene EDTA DTPA, diethylenetriamine pentaacetic acid EDDDA, ethylene diamine-/V,/V -diacetic-/V,/V -dipropionic acid EDDA, /V,/V -ethylene diamine diacetic acid CyDTA, cyclohexylene diamine tetraacetic acid. 

The free ion, Cu2+, appears to be the major species of Cu taken up by plants (Graham, 1981 Jones and Jarvis, 1981). Hence Cu complexation will decrease uptake (DeKock and Mitchell, 1957) unless the complex can dissociate and/or diffuse quickly enough to maintain a constant supply of Cu2+ at the root surface. In the case of Zn, the presence of humic acid (Chen and Aviad, 1990) and carboxylic acids (EDTA, diethylenetriamine pentaacetic acid (DTPA), nitrilotriacetic acid (NTA) DeKock and Mitchell, 1957) has been found to decrease absorption but it is not known whether Zn uptake is correlated with Zn2+ in solution because Zn speciation was not estimated. Other work has shown that Zn initially complexed with citrate is taken up by barley from nutrient solutions (Chairidchai and Ritchie, 1993) and the presence of chelates (EDTA, citrate) can speed up the diffusion of Zn to a root surface in soils (Hodgson et al., 1967 Elgawhary et al., 1970). Speciation in solution is particularly important in the uptake of iron because of its extremely low solubility in the absence of complexing anions... 

There is a close relationship between the metabolism of the shoot and the root. It is generally accepted that the xylem forms the main path for upward movement of water and ions from the roots to the leaves. Most of the essential major elements are transported in the xylem as inorganic ions. Nitrogen may be transported along the xylem as N03 if it is present in the external solution as nitrate. However, the plant sap may also contain organic nitrogen compounds such as amino acids. In the xylem, heavy metals will usually only be transported if special chelates are formed, eg, by citrate (Streit and Stumm, 1993). Iron is taken up and transported more readily when supplied as a chelated complex, such as ferric ethylenediamine tetraacetate (FeEDTA) or as ferric diethylenetriamine pentaacetate (FeDTPA) (Wallace and North, 1953). Calcium may also be transported in a chelated form (Jacoby, 1966). 

Cr Diethylenetriamine-pentaacetic acid Acetate buffer 4 x ht10 37... 

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