Dicyclohexylmethane-4,4 -diisocyanate HMDI

Polyurethanes (PUs), one of the most commonly used polymers for various blood-contacting biomedical applications, are generally prepared by the polycondensation reactions of diisocyanates with diols or amines [35, 36]. Reactions of diisocyanates with diols result in the formation of urethane linkages while diisocyanates reactions with amines result in urea linkages. Both aliphatic, as well as aromatic diisocyanate monomers, are commonly used for preparing polyurethane biomaterials. Examples include 1,4-butane diisocyanate (BDI), 1,6-hexamethylene diisocyanate (HDI), 4,4-dicyclohexylmethane diisocyanate (HMDI), and 4,4-diphenylmethane diisocyanate (MDl) [37]. Commonly used diols (or termed as polyols) for preparing polyurethanes includes poly ethers, polycaprolactone, and polyesters with molecular weights up to 5000 Da. 

Polymer Synthesis. Polyethylene glycol (PEG) 600,1000, and 1500 were obtained from Aldrich Chemical Company and dried by azeotroping with toluene. Molecular weights for the polyethylene glycols were determined from hydroxyl numbers. DieSiylene glycol (DEG) from Fisher Scientific was purified by vacuum distillation over metallic sodium. Hexamethylene diisocyanate (HMDI) from Aldrich Chemical Company was vacuum distilled. Dicyclohexylmethane-4,4 -diisocyanate (DCDI) (Desmodur W) from Mobay Chemical Company was used as received. Dibutyltin bis-(2-ethylhexanoate) from Kodak was stored over phosphorus pentoxide. N,N-dimethylformamide (DMF) from EM Science and 4-methyl-2-pentanone from Aldrich Chemical Company were dried over 3A molecular sieves. 

ABA ABS ABS-PC ABS-PVC ACM ACS AES AMMA AN APET APP ASA BR BS CA CAB CAP CN CP CPE CPET CPP CPVC CR CTA DAM DAP DMT ECTFE EEA EMA EMAA EMAC EMPP EnBA EP EPM ESI EVA(C) EVOH FEP HDI HDPE HIPS HMDI IPI LDPE LLDPE MBS Acrylonitrile-butadiene-acrylate Acrylonitrile-butadiene-styrene copolymer Acrylonitrile-butadiene-styrene-polycarbonate alloy Acrylonitrile-butadiene-styrene-poly(vinyl chloride) alloy Acrylic acid ester rubber Acrylonitrile-chlorinated pe-styrene Acrylonitrile-ethylene-propylene-styrene Acrylonitrile-methyl methacrylate Acrylonitrile Amorphous polyethylene terephthalate Atactic polypropylene Acrylic-styrene-acrylonitrile Butadiene rubber Butadiene styrene rubber Cellulose acetate Cellulose acetate-butyrate Cellulose acetate-propionate Cellulose nitrate Cellulose propionate Chlorinated polyethylene Crystalline polyethylene terephthalate Cast polypropylene Chlorinated polyvinyl chloride Chloroprene rubber Cellulose triacetate Diallyl maleate Diallyl phthalate Terephthalic acid, dimethyl ester Ethylene-chlorotrifluoroethylene copolymer Ethylene-ethyl acrylate Ethylene-methyl acrylate Ethylene methacrylic acid Ethylene-methyl acrylate copolymer Elastomer modified polypropylene Ethylene normal butyl acrylate Epoxy resin, also ethylene-propylene Ethylene-propylene rubber Ethylene-styrene copolymers Polyethylene-vinyl acetate Polyethylene-vinyl alcohol copolymers Fluorinated ethylene-propylene copolymers Hexamethylene diisocyanate High-density polyethylene High-impact polystyrene Diisocyanato dicyclohexylmethane Isophorone diisocyanate Low-density polyethylene Linear low-density polyethylene Methacrylate-butadiene-styrene... 

Synonyms/Trade Names Dicyclohexylmethane 4,4 -diisocyanate DMDi bis(4-isocyanatocyciohexyi)methane HMDI Hydrogenated MDI Reduced MDI Saturated MDI ... 

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