Dictyostelium cells hormone secretion

Goldbeter, A. 1987b. Periodic signaling and receptor desensitization from cAMP oscillations in Dictyostelium cells to pulsatile patterns of hormone secretion. In Temporal Disorder in Human Oscillatory Systems. L. 

The three best-known examples of biochemical oscillations were found during the decade 1965-1975 [40,41]. These include the peroxidase reaction, glycolytic oscillations in yeast and muscle, and the pulsatile release of cAMP signals in Dictyostelium amoebae (see Section V). Another decade passed before the development of Ca " " fluorescent probes led to the discovery of oscillations in intracellular Ca +. Oscillations in cytosolic Ca " " have since been found in a variety of cells where they can arise spontaneously, or after stimulation by hormones or neurotransmitters. Their period can range from seconds to minutes, depending on the cell type [56]. The oscillations are often accompanied by propagation of intracellular or intercellular Ca " " waves. The importance of Ca + oscillations and waves stems from the major role played by this ion in the control of many key cellular processes—for example, gene expression or neurotransmitter secretion. 

Second oscillator in cell cycle, 413,448-51 in Dictyostelium, 218 in glycolysis, 85,160 Secretion, of hormones, see Glucagon Gonadotropin-releasing hormone Growth hormone Insulin pulsatile secretion... 

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