Dichloro diethyl ether

Chlorex (1) A process for extracting lubricating oil stocks from petroleum fractions using 0,0-dichloro diethyl ether. Chlorex is also the trademark for this compound. Developed by Standard Oil Company (Indiana) in the early 1930s and used until the 1960s. 

Synonym 2-chloroethyl ether, l,l-oxybis(2-chloroethane), bis((3-chloroethyl)ether, Chlorex, l-chloro-2-(P-chloro-ethoxy)-ethane, -dichloroethyl ether, 2,2 -dichloroethyl ether, di(2-chloroethyl)ether, di(chloroethyl)ether, dichloro-diethyl ether, sym-dichlorodiethyl ether... 

ETHER DICHLORE (French) (111-44-4) see dichlorodiethyl ether or 2,2 -dichloro-diethyl ether. 

Distribution coefficients Di. of 10- can be achieved when pertcchnetate in 1 M H2SO4 is extracted w ith triphenylguanidinium chloride dissolved in /),/ -dichloro-diethyl ether. D ic decreases with increasing H2SO4 concentration, similar to Dr - The separation of TcOj from RcOj and even from MoOj is not possible by a single-stage extraction [146]. 

Bis(2-chloroethylthio)diethyl Ether 2,2/-Dibromodiethyl Sulfide 2,2/-Dichloro-2"-fluorotriethylamine 2,2/-Dichloroethyl Sulfide... 

Dissolve a small portion (1-3 mg) of the substance you want to chromatograph in any solvent that dissolves it and evaporates rapidly. Dichloro-methane or diethyl ether often works best. 

Other solvents that have been used are isopropanol [21], dichloro-methane/methanol [22], methanol/diethyl ether (10 1) with hydrochloric acid [23] for alkylphenols, dichloromethane [24-26], and hexane [27] for alkylphenols and short-chain NPEO, and hexane/ isopropyl alcohol for NP and NPEOi 9 [5]. 

The geminal dihalogenated cyclopropane derivatives 83a and 83b were lithiated by Vlaar and Klumpp . 7,7-Dichloro- (83a) and 7,7-dibromonorcarane (83b) were reacted with four equivalents of LiDBB in diethyl ether and several reaction conditions were examined by the authors such as reaction temperatures, the influence of different coordinating additives as well as various methods (Scheme 31). The achieved maximum yield for the geminal dilithium compound 84 was 55% (from 83b). Side-products, like the 1,2-dilithioethane derivative 85, the dilithiated dicyclohexylacetylene 86 or 1,3-dilithium compound 87, were observed in different quantities, sensitively depending on the reaction conditions. Also, carbenoid intermediates were formed as verified by trapping reactions (deuteriolysis). 

Di-p-chloro-bis(i74-l,5-cyclooctadiene)dirhodium(I) is a yellow-orange, air-stable solid. It can be used directly as obtained for preparative purposes5 or as a precursor for homogeneous catalysts.3,4 It can be recrystallized from dichloro-methane-diethyl ether to give orange prisms. The compound is soluble in dichloro-methane somewhat less soluble in acetone and insoluble in pentane and diethyl ether. Characteristic strong bands occur in the infrared spectrum at 819, 964, and 998 cm 1 (Nujol mull). The cyclooctadiene vinylic protons resonate in the 1H NMR spectrum at t 5.7 and the allylic protons at t 7.4-8.3 (deuteriochloroform solution). Other physical properties are given by Chatt.1... 

Dehalogenation has also been employed in the preparation of cyclobutenes. For example, stereoisomerically pure l,2-dichloro-3,4-dibromocyclobutane (18) reacts with 0.5% lithium amalgam in diethyl ether to give the nnf/ -tricyclooctadiene 32, which is isolated as its corresponding disilver(I) complex 31.11 However, similar treatment only converts tetrachlorocy-clobutane (16) to yyn-tricyclooctadiene 34 in very low yield.11... 

Boron trifluoride and boron trifluoride-diethyl ether complex can be used as a source of fluoride ions in the presence of hypobromites and hypochlorites, e.g. methyl hypobromitc, tert-butyl hypobromite, methyl hypochlorite in carbon tetrachloride at 25 C. The addition of bromine monofluoride" and chlorine monofluoride" to various alkenes is accompanied by the formation of the corresponding alkoxybromides and alkoxychlorides which hinder the isolation of the halofluorinated products.57 jV-Bromo- and A -chloro-substiluted alkyl- and arylamines. -amides, and -imides, A -chloro-A,-methylamine, A -bromo-A -methylamine, A -chloro-A, /V-dimethylamine, A-bromo-A.A-dimethylamine, ACV-dichloro-A -methylamine, V,fV-dibromo-,V-mcthylaminc, A -bromosuccinimide, -V-chlorosuccinimide, Af-bromoacct-amide, A.A -dichlorourethane, can be used in the reaction instead of the hypohalites. The reactions with various alkenes conducted in dichloromethane at room temperature in the presence of boron trifluoride-diethyl ether complex produce bromofluoro and chlorofluoro addition products in 40-80 % yield. However, the reactions are complicated by the addition of A -halo-succinimides and Af.A-dichlorourcthane to the C = C bonds.58... 

C. (2R,4R)-1,2 4,5-Diepoxypentane. A 1-L, round-bottomed flask with a magnetic stirrer bar is charged with (2R,4R)-1,5-dichloro-2,4-pentanediol (6.00 g, 34.7 mmol) and diethyl ether (270 mL), and the solution is cooled to 0°C. Freshly powdered potassium hydroxide (KOH, 18.5 g, 330 mmol) is added and the solution is... 

The following chemicals were obtained from Aldrich Chemical Company, Inc. and used without further purification 1,3-dimethoxybenzene (99%) butyl lithium (1.6 M in hexanes) 1-formylpiperdine (99%) boron trifiuoride-diethyl ether (purified, redistilled) 2,3-dichloro-5,6-dicyano-l,4-benzo-quinone (98%), and pyridine hydrochloride (98%). All solvents were reagent grade and were obtained from Fisher Scientific and used without further purification except where noted. Silica gel (230-400 mesh) was obtained from EM Scientific. Chloroform was stored over activated, 4-A molecular sieves for at least 24 h prior to use. Tetrahydrofuran (optima grade) was distilled from sodium benzophenone. Pyrrole (99%) was obtained from Aldrich Chemical Company, Inc. and distilled from calcium hydride. 

Citronellol 1 (3.2 mmol, 0.500 g), Se02 (1.6 mmol, 0.176 g) and t-BuOOH (70%, 4.48 mmol, 0.576 g) were dissolved in a small amount of dichloro-methane. Silica (1 g) was then added to form a slurry and excess solvent was evaporated off to obtain free flowing silica which was then exposed to micro-wave irradiation at power level 9 (640 W) for 10 min. Diethyl ether was then added and the mixture filtered. The filtrate was then washed (10% KOH, brine) and then dried (anhydrous Na2S04). The solvent was evaporated to furnish the pure product in 83% yield. 

From the reaction mixture of dichloroketene, obtained from dichloro-acetyl chloride with triethylamine in situ, and N-(2-pyridyl)formimidates 187 in diethyl ether or in 1,2-dimethoxyethane, the following were isolated by column chromatography 3-chloro-2-ethoxy-4//-pyrido[ 1,2-a]-... 

The cyclocondensation of Schiff bases 198 in diethyl ether and dichloro-... 

A drawback of the resulting intrinsic volume is that it does not distinguish between isomers, not only geometrical ones, such as 1,1-dichloro- and 1,2- dichloroethane, both having Vx = 63.5 cm3 mol 1, but also structural ones, such as 1-butanol and diethyl ether, both having Vx = 73.1 cm3 mol1. The Vx values, shown in Table 3. 4, are nearly proportional to the van der Waals intrinsic... 

Ru(methallyl)2(cyclooctadiene) is prepared by addition of polymeric dichloro(cy-clooctadiene)ruthenium to a suspension of (2-methylpropenyl)magnesium chloride in diethyl ether, and stirring at room temperature for 1.5 h. After hydrolysis with cold water at -40 °C, the reaction mixture is extracted twice with diethyl ether. Evaporation of the solvent furnishes a gray powder in 80 % yield. This complex (2.0 g, 6.26 mmol) and 2.6 g (6.10 mmol) l,3-bis(diphenylphosphino)butane are... 

The reaction of ferrocenecarbaldehyde (98) and resorcinol (99) under acidic conditions gave the phenolic macrocycle (100), which on addition of chlorobromomethane in the presence of a base produced the first redox-active cavitand (141,142) (101) (Scheme 31). An X-ray structural investigation on crystals of (101), obtained from a dichlorometh-ane-diethyl ether solvent mixture, revealed the inclusion of a dichloro-methane guest molecule within the cavitand host cavity (Fig. 23). Related redox-active cavitand host molecules ((102) and (103)) containing ferrocene moieties lining the wall of the cavitand cavity have also been prepared by our group (141, 142). 

Uses The technical p,p -DDT is a waxy solid, but in its pure form, it appears as colorless crystals. It is a mixture of three isomers p,p -DDT isomer (approximately 85%), ,//-DDT, and 0,0 -DDT (in smaller levels). DDT is soluble in solvents such as cyclohexanone, dioxane, benzene, xylene, trichloroethylene, dichloromethane, acetone, chloroform, and diethyl ether. It also is soluble in ethanol and methanol. The USEPA has grouped DDT under restricted use pesticide (RUP). Two similar chemicals that sometimes contaminate DDT products are DDE (l,l-dichloro-2,2-bis(chlorophenyl) ethylene) and DDD (1,1-dichloro-2,2-bis(p-chlorophenyl) ethane). DDD also was used to kill pests, but its use has been banned. One form of DDD has been used medically to treat cancer of the adrenal gland, but DDE has no commercial use.14,35... 

Lithium benzenetellurolate reacted with pentacarbonyl(diethylaminomethylidyne)-chromium tetrafluoroborate with addition of the benzenetellurolate anion to the carbyne C-atom. Heating the resulting pentacarbonyl[dicthylamino(phenyltelluro)methyl-ene]chromium with triphenylphosphane in acetone or with carbon monoxide in dichloro-methane produced carbonyl(diethylaminomethylidyne)benzenetellurolatochromium derivatives. Tetracarbonyl(diethylaminomethylidyne)benzenetellurolatochromium lost two molecules of carbon monoxide in diethyl ether at room temperature and formed a... 

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