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Propranolol Diazepam

Overdoses of cocaine are often rapidly fatal, victims dying within minutes from arrhythmias, seizures, or respiratory depression. Those who survive for 3 hours usually recover fully. Intravenous administration of diazepam, propranolol, or calcium channel-blocking drugs may be the best... [Pg.731]

Microsomal oxidative reactions constitute the most prominent phase I biotransformation pathway for a wide variety of structurally unrelated drugs (Table 1.4). Some drugs (e.g. amphetamine, diazepam, propranolol, lignocaine) simultaneously undergo more than one type of microsomal-mediated oxidative reaction. Microsomal enzymes are located primarily in liver cells, where they are associated with the smooth-surface (without ribosomes) endoplasmic reticulum (Fouts, 1961). Lipid solubility is a prerequisite for drug access to the... [Pg.10]

Changes in the protein binding of diazepam, propranolol, quini-dine and verapamil caused by heparin do not appear to be of clinical importance. [Pg.461]

Bailly D, Servant D, Blandin N, et al Effects of beta-blocking drugs in alcohol withdrawal a double-blind comparative study with propranolol and diazepam. Bio-med Pharmacother 46 419—424, 1992... [Pg.42]

Carlsson C, Fasth BG A comparison of the effects of propranolol and diazepam in alcoholics. Br J Addict Alcohol Other Drugs 71 321-326, 1976... [Pg.42]

Cantopher T, Olivieri S, Cleave N, et al Chronic benzodiazepine dependence a comparative smdy of abrupt withdrawal under propranolol cover versus gradual withdrawal. Br J Psychiatry 156 406-411, 1990 Caplan RD, Andrews FM, Conway TL, et al Social effects of diazepam use a longitudinal field study. Soc Sci Med 21 887—898, 1985 Charney DA, Paraherakis AM, Gill KJ The treatment of sedative-hypnotic dependence evaluating clinical predictors of outcome. J Clin Psychiatry 61 190—195, 2000... [Pg.150]

Mood stabilizers phenytoin, valproate, topiramate Sedative/anxiolytics diazepam, barbiturates Beta-blockers propranolol... [Pg.93]

Fig. 4.3 CSF concentration/free (unbound) plasma concentration ratios for neutral and basic drugs 1, ritropirronium 2, atenolol 3, sulpiride 4, morphine 5, cimetidine 6, meto-prolol 7, atropine 8, tacrine 9, digoxin 10, propranolol 11, carbamazepine 12, ondansetron 13, diazepam 14, imipramine 15, digitonin 16, chlorpromazine and acidic drugs, a, salicylic acid b, ketoprofen c, oxyphenbutazone and d, indomethacin compared to log D. Fig. 4.3 CSF concentration/free (unbound) plasma concentration ratios for neutral and basic drugs 1, ritropirronium 2, atenolol 3, sulpiride 4, morphine 5, cimetidine 6, meto-prolol 7, atropine 8, tacrine 9, digoxin 10, propranolol 11, carbamazepine 12, ondansetron 13, diazepam 14, imipramine 15, digitonin 16, chlorpromazine and acidic drugs, a, salicylic acid b, ketoprofen c, oxyphenbutazone and d, indomethacin compared to log D.
Ciprofloxacin (Cipro, Cipro XR, Proquin XR) [Antibiotic/ Fluoroquinolone] Uses Rx lower resp tract, sinuses, skin skin structure, bone/joints, urinary tract Infxns including prostatitis Action Quinolone antibiotic DNA gyrase Dose Adults. 250-750 mg PO ql2h XR 500-1000 mg PO q24h or 200-400 mg IV ql2h in renal impair Caution [C, /-] Children <18 y Contra Component sensitivity Disp Tabs, susp, inj SE Restlessness, N/V/D, rash, ruptured tendons, T LFTs Interactions T Effects Wf probenecid T effects OF diazepam, theophylline, caffeine, metoprolol, propranolol, phenytoin, warfarin effects W/ antacids, didanosine, Fe salts. Mg, sucralfate, Na bicarbonate,... [Pg.112]

Noyes R Jr, Anderson DJ, Clancy J, et al. Diazepam and propranolol in panic disorder and agoraphobia. Arch Gen Psychiatry 1984 41 287-292. [Pg.269]

Omeprazole can inhibit the metabolism of drugs metabolised mainly by the cytochrome P-450 enzyme subfamily 2C (diazepam, phenytoin), but not of those metabolished by subfamilies lA (caffeine, theophylline), 2D (metoprolol, propranolol), and 3A (ciclosporin, lidocaine (lignocaine), quinidine). Since relatively few drugs are metabolised mainly by 2C compared with 2D and 3A, the potential for omeprazole to interfere with the metabolism of other drugs appears to be limited, but the half lives of diazepam and phenytoin are prolonged as much as by cimetidine. [Pg.187]

C19 Diazepam, S-mephenytoin, naproxen, nirvanol, omeprazole, propranolol Barbiturates, rifampin /3-benzylnirvanol, N3- benzylphenobarbital, fluconazole... [Pg.82]

The cardiac arrhythmias are life-threatening, so the patient must be closely monitored, with facilities available for possible resuscitation. Drugs such as quinidine and procainamide are contraindicated, but lidocaine, propranolol, or phenytoin has been used safely and effectively. The arterial blood gas levels, pH, and electrolyte concentrations should be monitored so that metabolic acidosis or hypokalemia can be identified that would further aggravate the arrhythmias. Electrical pacing may be required if the antiarrhythmic drugs fail. Hyperpyrexia is treated by cooling. Seizures may be managed by intravenous doses of diazepam. [Pg.423]

Diazepam, buspirone, propranolol and diphenhydramine all reduce anxiety... [Pg.604]

M. Hori, S. Satoh, H. I. Maibach, and R. H. Guy, Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro effect of enhancer lipophilic-ity. J. Pharm. Sci. 80 32-35 (1991). [Pg.168]

See other pages where Propranolol Diazepam is mentioned: [Pg.250]    [Pg.1381]    [Pg.16]    [Pg.12]    [Pg.588]    [Pg.3948]    [Pg.61]    [Pg.462]    [Pg.250]    [Pg.1381]    [Pg.16]    [Pg.12]    [Pg.588]    [Pg.3948]    [Pg.61]    [Pg.462]    [Pg.1724]    [Pg.613]    [Pg.1102]    [Pg.759]    [Pg.22]    [Pg.128]    [Pg.112]    [Pg.226]    [Pg.228]    [Pg.238]    [Pg.313]    [Pg.190]    [Pg.1384]    [Pg.1102]    [Pg.112]    [Pg.226]    [Pg.228]    [Pg.238]    [Pg.351]    [Pg.245]    [Pg.650]    [Pg.204]    [Pg.602]    [Pg.40]    [Pg.114]   
See also in sourсe #XX -- [ Pg.723 ]



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