Diarrhea docetaxel

Docetaxel Myelosuppression, severe fluid retention Alopecia, fatigue, stomatitis, nausea, vomiting, diarrhea, peripheral neuropathy, nail disorder, skin reactions, hypersensitivity reactions... [Pg.1313]

Cisplatin-docetaxel diarrhea, cardiac toxicity, renal toxicity, neuropathy, weakness, hypersensitivity reactions, anemia Infection, thromocytopenia, nausea, vomiting, diarrhea, cardiac, High (day 1 only)... [Pg.1330]

Gemcitabine-docetaxel Nausea and vomiting, diarrhea, thrombocytopenia, asthenia, Moderate... [Pg.1330]

Docetaxel -semisynthetic taxane stabilizes tubulin polymers leading to death of mitotic cells -bone marrow suppression -nausea and vomiting -mucocutaneous effects (mucositis, stomatitis, diarrhea) -hypersensitivity reactions -fluid retention syndrome -fatigue -myalgias -alopecia (universal)... [Pg.171]

Generic Name Docetaxel Trade Name Taxotere Primary Antineoplastic Indication(s) Breast cancer Common Adverse Effects Blood disorders (anemia, leukopenia, neutropenia] fever fluid retention paresthesias/dysthesias skin rash-es/itching stomatitis Gl distress (nausea, diarrhea] ... [Pg.575]

Metabolism/elimination Hepatic metabolism Adverse reactions Alopeda, nausea/vomiting/diarrhea, myelosuppression (dose-limiting, granulocytopenia, and thrombocytopenia), hepatic toxidty, peripheral neuropathy, hypersensitivity reactions, myalgias/arthralgias, rare cardiovascular events, fluid retention/pulmonary edema (docetaxel). [Pg.150]

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