Diabetes mellitus type management

The other type of diabetes mellitus, type II, is far more common. In contrast, type II is not an autoimmune process and may or may not be insulin dependent that is, a diabetic state that is most effectively managed by insulin therapy. Frequently, NIDDM is used interchange-... 

For the first time in history there was clear, unambiguous clinical evidence, in humans, that symptoms of diabetes mellitus could be controlled with the exogenous administration of the active factor of the pancreas—insulin. Thus, replacement therapy with the newly discovered hormone, insulin, had arrested what was clearly an otherwise fatal metabolic disorder. From that point forward, diabetes mellitus (type 1) became a manageable disease by pharmacological intervention. 

McKeage K, Goa KL. Insulin glargine a review of its therapeutic use as a long-acting agent for the management of type 1 and 2 diabetes mellitus. Drugs 2001 61 1599-624. 

There is considerable overlap in outcomes of ACE-Is and ARBs in the management of Type 2 diabetes mellitus. Use the most efficacious class of drug according to patient circumstances. 

Diabetes mellitus is a heterogeneous group of disorders characterized by abnormalities in carbohydrate, protein, and lipid metabolism. The central disturbance in diabetes mellitus is an abnormality in insulin production or action or both, although other factors can be involved. Hyperglycemia is a common end point for all types of diabetes mellitus and is the parameter that is measured to evaluate and manage the efficacy of diabetes therapy. 

The sulfonylureas are ineffective for the management of type I and severe type II diabetes mellitus, since the number of viable -cells in these forms of diabetes is small. Severely obese diabetics often respond poorly to the sulfonylureas, possibly because of the insulin resistance that often accompanies obesity. 

Rosenstock 1. Management of type 2 diabetes mellitus in the elderly special considerations. Drugs Aging 2001 18 31-44. 

It is indicated in the management of type II diabetes mellitus in patients who are not responding to diet and exercise. 

Ryan, C.M., and D.J. Becker, Tlypoglycemia in children with type 1 diabetes mellitus. Risk factors, cognitive function, and management. Endocrinol Metab Clin North Am, 1999. 28(4) 883-900. 

Kaplan NM Management of hypertension in patients with type 2 diabetes mellitus Guidelines based on current evidence. Ann Intern Med 2001 135 1079. [PMID 11747387]... 

Mudaliar S et al New oral therapies for type 2 diabetes mellitus The glitazones or insulin sensitizers. Annu Rev Med 2001 52 239. [PMID 11160777] Nathan DM et al Management of hyperglycemia in type 2 diabetes mellitus A consensus algorithm for the initiation and adjustment of therapy. Diabetes... 

Tupola S, Sipila I, Huttunen NP, Salo S, Nuuja A, Akerblom HK. Management of asymptomatic hypoglycaemia in children and adolescents with Type 1 diabetes mellitus. Diabet Med 2000 17(10) 752-3. 

Physical therapists and occupational therapists may help reinforce the importance of patient compliance during pharmacologic management of diabetes mellitus. Therapists can question whether patients have been taking their medications on a routine basis. Regular administration of insulin is essential in preventing a metabolic shift toward ketone body production and subsequent ketoacidosis, especially in patients with type 1 diabetes. In addition, therapists can help explain that adequate control of blood glucose not only prevents acute metabolic problems but also seems to decrease the incidence of the neurovascular complications. 

Lien LF, Angelyn Bethel M, Feinglos MN. In-hospital management of type 2 diabetes mellitus. Medical Clinics of North America 2004, 88, 1085-1105. 

Mr SA is 185 cm tall, weighs 83 kg and has a 15-year history of type 2 diabetes mellitus and hypercholesterolaemia. He is under the care of the diabetes clinic at the hospital for management of Charcot s arthropathy of the foot and diabetic foot ulcer. He also has a 5-year history of ischaemic heart disease and underwent coronary artery bypass grafting one year ago. He drinks half-a-bottle of red wine per day and smokes a pipe. He is allergic to penicillin. His current medications are ... 

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