Detection of DNA Strand Breaks

Gorczyca, W., Gong, J., and Darzynkiewicz, Z., Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick... [Pg.119]

Skare JA, Schrotel KR. 1984. Alkaline elution of rat testicular DNA Detection of DNA strand breaks after in vivo treatment with chemical mutagens. Mutat Res 130 283-294. [Pg.227]

Gorczyca, W, Melamed, M. R., and Darzyrikiewicz, Z. (1993) Apoptosis of S-phase HL-60 cells induced by topoisomerase inhibitors detection of DNA strand breaks by flow cytometry using the in situ nick translation assay Toxicol Lett 67, 249-258. [Pg.354]

Chen J, Jin K, Chen M, Pei W, Kawaguchi K, Greenberg DA, Simon RP (1997) Early detection of DNA strand breaks in the brain after transient focal ischemia implications for the role of DNA damage in apoptosis and neuronal cell death. J Neurochem 69 232-245... [Pg.68]

Migheli, A., Attanasio, A., and Schiffer, D. (1995) Ultrastructural detection of DNA strand breaks in apoptotic neural cells by in situ end-labelling techniques. [Pg.51]

The detection of DNA strand breaks requires cell prefixation with a crosslinking agent such as formaldehyde to prevent the extraction of low MW DNA during the procedure. Labeling DNA strand breaks with FITC is... [Pg.49]

Rajapakse, N., Butterworth, M., and Kortenkamp, A. (2005) Detection of DNA strand breaks and oxidized DNA bases at the single-cell level resulting from exposure to estradiol and hydroxylated metabolites. Environ. Mol. Mutagen., 45, 3974-04. [Pg.196]

Birnboim HC, Jevcak JJ (1981) Fluorometric method for rapid detection of DNA strand-breaks in human white blood cells produced by low doses of radiation. Cancer Res 41 1889-1892... [Pg.319]

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