Depression MAOIs

Uses Allergic Rxns itching Action Phenothiazine antihistamine serotonin antagonist Dose Adults. 4-20 mg PO qSh max 0.5 mg/kg/d Feds. 2-6 y 2 mg bid-tid (max 12 mg/24 h) 7-14 y 4 mg bid-tid in hepatic impair Caution [B, ] BPH Contra Neonates or <2 y NAG BOO acute asthma GI obst Disp Tabs, syrup SE Anticholinergic, drowsiness Interactions T Effects Wf CNS depressants, MAOIs, EtOH X effects OF epi, fluoxetine EMS Use other CNS depressants w/ caution concurrent EtOH use can T CNS depression higher epi doses may be needed if used OD May cause mood changes, Szs, CNS depression, or CNS stimulation symptomatic and supportive... 

Flistrionic personality disorder is similar to the syndrome that Liebowitz and Klein ( 259) have termed hysteroid dysphoria or atypical depression. MAOIs have proven to be very helpful in this condition and these data are reviewed in Chapter 7. As noted earlier, Rifkin et al. (242) also investigated the effects of antidepressants in patients with emotionally unstable personalities, a syndrome characterized by excitability and ineffectiveness when confronted with minor stress. This syndrome is primarily found in female adolescents whose moods consist of the following ... 

Chlorzoxazone (Paraflex, Parafon Forte DSC, Others) [Skeletal Muscle Relaxant/ANS Drug] Uses Adjunct to rest physical therapy to relieve discomfort associated w/ acute, painful musculoskeletal conditions Action Centrally acting skeletal muscle relaxant Dose Adults. 250-500 mg PO tid-qid Peds. 20 mg/kg/d in 3-4 + doses Caution [C, ] Avoid EtOH CNS depressants Contra Severe liver Dz Disp Tabs SE Drowsiness, tach, dizziness, hepatotox, angioedema Interactions T Effects W/ antihistamines, CNS depressants, MAOIs, TCAs, opiates, EtOH, watercress EMS Use of CNS depressants and concurrent EtOH use can T sedation urine may turn reddish purple or orange OD May cause N/V/D, dizziness, HA, X deep tendon reflexes, hypotension and resp depression symptomatic and supportive, activated charcoal may be effective... 

Clemastine Fumarafe (Tavist, Dayhist, Antihist-1) [OTC] [Antihistamine] Uses Allergic rhinitis Sxs of urticaria Action Antihistamine Dose Adults Peds. >12 y 1.34 mg bid to 2.68 mg dd max 8.04 mg/d <6 y 0.335-0.67 mg/d into (max 1.34 mg/d) 2-3 d. 6-12 y 0.67-1.34 mg bid (max 4.02 /d) Caution [C, M] BOO do not take w/ MAOI Contra NAG Disp Tabs, syrup SE Drowsiness, dyscoordinadon, epigastric distress, urinary retendon Interactions T Effects V/ CNS depressants, MAOIs, EtOH i effects OF heparin, sulfonylureas EMS Use odier CNS depressants w/ caudon concuirent EtOH use can T CNS effects T risk of photosensidvity Rxns OD May cause CNS... 

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