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Deoxyribonucleic acid drugs

Deoxyribonucleic acid (drug-conjugate Cancer cells... [Pg.368]

Double bond, 14, 38-40, 170-172 Double helix, 1094—1096. See also Deoxyribonucleic acid Drugs. See also AIDS Antibiotics chiral, 273 generic names of, 63 Dyes, 896-897... [Pg.1224]

Dextrans (e.g., enzymc-drug-dcxtran conjugates) Deoxyribonucleic acid (lysosomotropic carrier)... [Pg.568]

The discovery of the base-paired, double-helical structure of deoxyribonucleic acid (DNA) provides the theoretic framework for determining how the information coded into DNA sequences is replicated and how these sequences direct the synthesis of ribonucleic acid (RNA) and proteins. Already clinical medicine has taken advantage of many of these discoveries, and the future promises much more. For example, the biochemistry of the nucleic acids is central to an understanding of virus-induced diseases, the immune re-sponse, the mechanism of action of drugs and antibiotics, and the spectrum of inherited diseases. [Pg.215]

Drug X is an ami mycobacterial agent that inhibits other bacteria as well as poxviruses. However, it should not be used as a single agent because resistant mutants frequently form. The responsible mutation may alter the site of action of drug X [i.e., the deoxyribonucleic acid (DNA)-dependent ribonucleic acid (RNA) polymerase]. What is drug X ... [Pg.60]

Drug Master File deoxyribonucleic acid design qualification effective dose... [Pg.437]

Deoxyribonucleic acid (DNA) serves as a template for the synthesis of nucleic acids. Ribonucleic acid (RNA) executes protein synthesis and thus permits cell growth. Synthesis of new DNA is a prerequisite for cell division. Substances that inhibit reading of genetic information at the DNA template damage the regulatory center of cell metabolism. The substances listed below are useful as antibacterial drugs because they do not affect human cells. [Pg.274]

DMMS—drug-metabolizing microsomal system DNA—deoxyribonucleic acid dopa/DOPA/Dopa—(3,4-dlhydroxyphenylalanine)... [Pg.275]

Jin C, Miners JO, Lillywhite KG, et al. Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs. J Pharmacol Exp Ther 1993 264... [Pg.119]

Information concerning the method of manufacture may be presented in the form of a flow chart. Supply a brief description of the methods of isolation (e.g., synthetic process, fermentation, extraction, recombinant deoxyribonucleic acid [DNA] procedure) and purification (solvent recrystallization, column chromatography, distillation). Include all synthetic pathways that have been adequately characterized during the investigational stages of drug development. [Pg.192]

The development of recombinant deoxyribonucleic acid (DNA) technology has allowed the emergence of novel applications such as drug production directly in the... [Pg.565]

Diuretic A drug that promotes the excretion of salt and water by the kidney Diurnal A reaction that is recurring daily DNA Deoxyribonucleic acid (see Chromosome)... [Pg.205]

See other pages where Deoxyribonucleic acid drugs is mentioned: [Pg.1957]    [Pg.1957]    [Pg.672]    [Pg.570]    [Pg.284]    [Pg.375]    [Pg.128]    [Pg.94]    [Pg.121]    [Pg.204]    [Pg.57]    [Pg.441]    [Pg.155]    [Pg.395]    [Pg.1125]    [Pg.6]    [Pg.362]    [Pg.8]    [Pg.301]    [Pg.272]    [Pg.87]    [Pg.539]    [Pg.804]    [Pg.1329]    [Pg.82]    [Pg.2]   
See also in sourсe #XX -- [ Pg.237 ]



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