Chemoattractant Receptors

Cheese Reaction Chemical Chaperone Chemical Library Chemical Neurotransmission Chemoattractant Receptors Chemokine Receptors Chemokines... 

Locati M, Torre YM, Galliera E, et al. Silent chemoattractant receptors D6 as a decoy and scavenger receptor for inflammatory CC chemokines. Cytokine Growth Factor Rev 2005 16 679-686. 

Murphy, P. M., Gallin, E. K., Tiffany, H. L., Malech, H. L. (1990). The formyl peptide chemoattractant receptor is encoded by a 2 kilobase messenger RNA. Expression in Xertopus oocytes. FEBS Lett. 261,353-7. 

Huang, J. L., Gao, P. S., Mathias, R. A., et al. (2004) Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability. Hum. Mol. Genet. 13, 2691-2691. 

The purpose of this assay is to detect saturable chemoattractant binding to specific chemoattractant receptors on leukocytes. A chemoattractant (fluorochrome... 

Murphy, P. M. (1994) The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12, 593-633. 

Zagorski, J. and Wahl, S. M. (1997) Inhibition of acute peritoneal inflammation in rats by a cytokine induced neutrophil chemoattractant receptor antagonist. J. Immunol. 159, 1059-1062. 

Koo, C., Lefkowitz, R.J., and Snyderman, R. (1983). Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes. J. Clin. Invest. 72, 748-753. 

Prossnitz, E. R., and Ye, R. D. (1997). The N-formyl peptide receptor A model for the study of chemoattractant receptor structure and function. Pharmacol. Ther. 74, 73-102. 

Seifert, R., and Wenzel-Seifert, K. (2001b). Unmasking different constitutive activity of four chemoattractant receptors using Na+ as universal stabilizer of the inactive (R) state. Receptors Channels 7, 357—369. 

G. Servant, O. D. Weiner, P. Heizmark, T. Balia, J. W. Sedat, and H. R. Bourne. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science, 287, 1037- 1040, 2000. 

Since all peripheral blood neutrophils have chemoattractant receptors for N-formyl peptide, the entire population of neutrophils should exhibit a concentration-dependent shift in fluorescence intensity when exposed to FP-Fl. The mean channel values of the normal distribution fluorescence histograms are recorded and plotted vs the concentration of fluorescent FMLPK-Fl (Fig. 2). The data presented in Fig. 2 are from an... 

The platelet activating factor receptor as a GPCR (rhodopsin family) is possibly also a promiscuous receptor for CKs. The same can be considered for the chemoattractant receptors, complement 5 anaphylatoxin receptor, and FPR/FMLPR (N-formyl peptide receptor). 

Wang J, Xu Y, Zhao H et al (2009) Genetic variations in chemoattractant receptor expressed on Th2 cells (CRTH2) is associated with asthma susceptibility in Chinese children. Mol Biol Rep 36 1549-1553... 

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