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Death-signal transduction system

The release of cytochrome c from mitochondria to the cytosol is thought to be a key event for signal transduction in the apoptotic process. It has been suggested that it induces a series of biochemical reactions that result in caspase activation and subsequent cell death. Tamaki et al. [12] have developed a microchip-based system for direct monitoring of cytochrome c distribution during the apoptosis process. This system incorporated microscale cell culture, chemical stimulation, and a scanning-thermal-... [Pg.1217]

The mechanisms by which allelochemicals exert their phytotoxic activity also vary, although the direct target for any of these phytochemicals are yet to be identified. Sorgoleone, for example, interferes with a number of essential processes such as nutrient uptake and electron transfer [52]. In contrast, (-)-catechin induces in the roots of susceptible species a wave of ROS (reactive oxygen species), which, through a signal transduction cascade, culminates in the death of the root system [49]. [Pg.275]


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See also in sourсe #XX -- [ Pg.22 ]

See also in sourсe #XX -- [ Pg.22 ]




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Signal transduction

Signal transduction system

Signaling transduction

Signalling systems

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