Death definition

The assumption If civilization endures, medical science should eventually be able to repair almost any damage to the human body, including freezing damage and senile debility or other cause of death. (Definite reasons for such optimism will be given.)... 

Sentencing Guidelines Council (2010) Corporate Manslaughter Health and Safety Offences Causing Death Definitive Guideline (London Crown). 

Once you re in the realm of Death, Death can sense your cares, your passions, your hopes, and your dreams. The dead have none of these. In some ways. Death definitely wants you killed. In other ways. Death doesn t want to kill you, for he longs to possess the kinds of feelings and life force you carry. 

Tb allium, which does not occur naturaHy in normal tissue, is not essential to mammals but does accumulate in the human body. Levels as low as 0.5 mg/100 g of tissue suggest thallium intoxication. Based on industrial experience, 0.10 mg /m of thallium in air is considered safe for a 40-h work week (37). The lethal dose for humans is not definitely known, but 1 g of absorbed thallium is considered sufficient to kHl an adult and 10 mg/kg body weight has been fatal to children. In severe cases of poisoning, death does not occur earlier than 8—10 d but most frequently in 10—12 d. Tb allium excretion is slow and prolonged. For example, tb allium is present in the feces 35 d after exposure and persists in the urine for up to three months. 

Arsine is extremely toxic and a potent hemolytic agent, ultimately causing death via renal failure. Numerous human case reports are available, but these reports lack definitive quantitative exposure data. The reports, however, affirm the extreme toxicity and latency period for the toxic effects of arsine in humans. 

Based upon the available data, derivation of AEGL-1 values was considered inappropriate. The continuum of arsine-induced toxicity does not appear to include effects consistent with the AEGL-1 definition. The available human and animal data affirm that there is a very narrow margin between exposures that result in little or no signs or symptoms of toxicity and those that result in lethality. The mechanism of arsine toxicity (hemolysis that results in renal failure and death), and the fact that toxicity in humans and animals has been reported at concentrations at or below odor detection levels (-0.5 parts per million (ppm)) also support such a conclusion. The use of analytical detection limits (0.01 to 0.05 ppm) was considered as a basis for AEGL-1 values but was considered to be inconsistent with the AEGL-1 definition. 

Women >55 years or premature menopause without estrogen-replacement therapy Family history of premature CHD (definite myocardial infarction or sudden death before 55 years of age in father or other male first-degree relative or before 65 years of age in mother or other female first-degree relative) Cigarette smoking... 

The DSM is careful to recognize that culture also determines definitions of mental illness. In the DSM, unusual and distressing behaviors such as culturally sanctioned responses to the death of a loved one are excluded from diagnosis. Most current conceptualizations of mental illness recognize that societal values play an important role in establishing whether something is a mental disorder (Lilienfeld Marino, 1995 Wakefield, 1992). The result is that the boundaries of mental illness are believed to shift as a function of culture, both across cultures and within cultures, over time. One important implication of cultural relativism is that definitions of mental illness will necessarily vary. 

Few data were available that met the definitions of AEGL end points. One inhalation study with 20 human subjects described headaches and slight loss of balance at exposure concentrations of 0.1 to 1.5 ppm for exposure durations of up to 8 h (Stewart et al. 1974). Acute exposure of monkeys for 6 h at concentrations ranging between 70 and 100 ppm resulted in severe signs of toxicity including convulsions but no deaths (Jones et al. 1972). In the same study, exposure of rats at a higher concentration, 189 ppm for 4 h, resulted in no toxic signs. Examination of the relationship between exposure duration and concentration for both mild and severe headaches in humans over periods of 1 to 8 h determined that the relationship is C xt=k. 

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