Datura stramonium anticholinergic effects

Seeds of Datura stramonium have anticholinergic effects, similar to those seen with trihexyphenidyl and benztropine (Ebadi and Pfeiffer, 2005). 

Tropane alkaloids, such as hyoscyamine and/or scopolamine, occur in the solanaceous plants Atropa belladonna, Datura stramonium, Hyoscyamus niger, and Mandragora officinarum. These alkaloids are powerful anticholinergic agents and can elicit peripheral symptoms (for example blurred vision, dry mouth) as well as central effects (for example drowsiness, delirium). They can potentiate the effects of anticholinergic medicaments. 

Nervous system Datura stramonium has been traditionally used in North America, East Asia, and Africa to treat asthma, chronic bronchitis, arthritis, and pain. All parts of the plant contain poisonous alkaloids, including atropine, hyoscyamine, and hyoscine (scopolamine). The highest concentration of anticholinergic alkaloids is present in the seeds (equivalent to 0.1 mg of atropine per seed). Adverse anticholinergic effects can occur [45 ]. 

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